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Mix23 Gene Detail
Summary
  • Symbol
    Mix23
  • Name
    mitochondrial matrix import factor 23
  • Synonyms
    A930007B11Rik, Ccdc58
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146423
    NCBI Gene: 381045
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:35892055-35912490 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    520 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146423
 protein coding gene Chr16:35892030-35912490 (+)
129S1/SvImJ ENSMUSG00200027904
 protein coding gene Chr16:32911418-32931848 (+)
A/J ENSMUSG00195010681
 protein coding gene Chr16:32463044-32483475 (+)
AKR/J ENSMUSG00220028559
 protein coding gene Chr16:32750854-32771285 (+)
BALB/cJ ENSMUSG00180012825
 protein coding gene Chr16:32678689-32699125 (+)
C3H/HeJ ENSMUSG00175030013
 protein coding gene Chr16:32815339-32835777 (+)
C57BL/6NJ ENSMUSG00215011717
 protein coding gene Chr16:32699816-32720258 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020712
 protein coding gene Chr16:33118801-33138524 (+)
CAST/EiJ ENSTCUG00005028038
 protein coding gene Chr16:33078084-33098495 (+)
CBA/J ENSMUSG00210026506
 protein coding gene Chr16:32872453-32892891 (+)
DBA/2J ENSMUSG00185022814
 protein coding gene Chr16:32775442-32795878 (+)
FVB/NJ ENSMUSG00205016557
 protein coding gene Chr16:32810784-32831215 (+)
JF1/MsJ ENSUMUG00000025269
 protein coding gene Chr16:32972936-32993270 (+)
LP/J ENSMUSG00230025092
 protein coding gene Chr16:35431489-35451919 (+)
NOD/ShiLtJ ENSMUSG00190022724
 protein coding gene Chr16:32971620-32992051 (+)
NZO/HlLtJ ENSMUSG00225037960
 protein coding gene Chr16:38530842-38551272 (+)
PWK/PhJ ENSLUMG00010028898
 protein coding gene Chr16:32876847-32897433 (+)
SPRET/EiJ ENSMSPG00010017037
 protein coding gene Chr16:32805472-32826263 (+)
WSB/EiJ ENSIUOG00005025509
 protein coding gene Chr16:32932099-32952347 (+)



Homology
more
  • Human Ortholog
    MIX23, mitochondrial matrix import factor 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIX23, mitochondrial matrix import factor 23
  • Synonyms
    CCDC58
  • Links
    NCBI Gene ID: 131076
    UniProt: Q4VC31

  • Chr Location
    3q21.1; chr3:122359587-122383239 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Female mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    60
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000075229 Ensembl Gene Model | MGI Sequence Detail 20436 C57BL/6J ±  kb
    transcript ENSMUST00000164916 Ensembl | MGI Sequence Detail 1073 Not Applicable  
    polypeptide ENSMUSP00000125874 Ensembl | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 60

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1925194, MGI:7414077
    References
    more
    • Summaries
      All 36
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:348425 Pham AH, et al., Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice. Cells. 2024;13(10):802
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory