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Tug1 Gene Detail
Summary
  • Symbol
    Tug1
  • Name
    taurine upregulated gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144114
    NCBI Gene: 544752
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3589313-3599021 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    154 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144114
 protein coding gene Chr11:3589313-3599673 (-)
129S1/SvImJ ENSMUSG00200028610
 protein coding gene Chr11:551195-552806 (-)
A/J ENSMUSG00195023109
 protein coding gene Chr11:458606-460223 (-)
AKR/J ENSMUSG00220008440
 protein coding gene Chr11:471768-473379 (-)
BALB/cJ ENSMUSG00180021681
 protein coding gene Chr11:481572-483183 (-)
C3H/HeJ ENSMUSG00175008978
 protein coding gene Chr11:471306-472917 (-)
C57BL/6NJ ENSMUSG00215029061
 protein coding gene Chr11:481653-483264 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013289
 unclassified non-coding RNA gene Chr11:467448-477405 (-)
CAST/EiJ ENSTCUG00005035411
 protein coding gene Chr11:570177-571793 (-)
CBA/J ENSMUSG00210017673
 protein coding gene Chr11:470954-472565 (-)
DBA/2J ENSMUSG00185017362
 protein coding gene Chr11:568661-570272 (-)
FVB/NJ ENSMUSG00205029125
 protein coding gene Chr11:447369-448980 (-)
JF1/MsJ ENSUMUG00000026211
 protein coding gene Chr11:726386-728002 (-)
LP/J ENSMUSG00230032049
 protein coding gene Chr11:1634374-1635985 (-)
NOD/ShiLtJ ENSMUSG00190031642
 protein coding gene Chr11:458487-460104 (-)
NZO/HlLtJ ENSMUSG00225025781
 protein coding gene Chr11:3691503-3693114 (-)
PWK/PhJ ENSLUMG00010018442
 protein coding gene Chr11:458324-459940 (-)
SPRET/EiJ ENSMSPG00010008194
 protein coding gene Chr11:541579-543203 (-)
WSB/EiJ ENSIUOG00005007419
 protein coding gene Chr11:472342-473953 (-)



Homology
more
  • Human Ortholog
    TUG1, taurine up-regulated 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUG1, taurine up-regulated 1
  • Synonyms
    LINC00080, NCRNA00080, TI-227H
  • Links
    NCBI Gene ID: 55000

  • Chr Location
    22q12.2; chr22:30969245-30979395 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a null allele are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    641
  • Tissues
    30
  • cDNA Data
    23
  • Literature Summary
    4
Sequences &
Gene Models
less
  • All Sequences
    63
  • RefSeq
    3
  • UniProt
    5
Representative SequencesLengthStrain/SpeciesFlank
genomic 544752 NCBI Gene Model | MGI Sequence Detail 9709 C57BL/6J ±  kb
transcript NM_001396521 RefSeq | MGI Sequence Detail 7084 C57BL/6  
polypeptide A0A6I8MX38 UniProt | EBI | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR043502 DNA/RNA polymerase superfamily
    IPR043128 Reverse transcriptase/Diguanylate cyclase domain
Molecular
Reagents
less
  • All nucleic 25
    cDNA 23
    Primer pair 1
    Other 1

    Microarray probesets 8
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:31358 Ishiguro T, et al., Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials. Cancer Res. 1996 Feb 15;56(4):875-9
  • Latest
    J:330985 Yin M, et al., LncRNA TUG1 Demethylated by TET2 Promotes NLRP3 Expression, Contributes to Cerebral Ischemia/Reperfusion Inflammatory Injury. ASN Neuro. 2021 Jan-Dec;13:17590914211003247
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory