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Gstt3 Gene Detail
Summary
  • Symbol
    Gstt3
  • Name
    glutathione S-transferase, theta 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143526
    NCBI Gene: 103140
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:75609949-75617248 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 38.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143526
 protein coding gene Chr10:75609949-75617256 (-)
129S1/SvImJ ENSMUSG00200041825
 protein coding gene Chr10:72311445-72318738 (-)
A/J ENSMUSG00195045473
 protein coding gene Chr10:72623554-72630854 (-)
AKR/J ENSMUSG00220041635
 protein coding gene Chr10:72283313-72290614 (-)
BALB/cJ ENSMUSG00180051589
 protein coding gene Chr10:72638026-72645326 (-)
C3H/HeJ ENSMUSG00175041476
 protein coding gene Chr10:72509374-72516673 (-)
C57BL/6NJ ENSMUSG00215049601
 protein coding gene Chr10:72246955-72254255 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015449
 protein coding gene Chr10:69806877-69814644 (-)
CAST/EiJ ENSTCUG00005050160
 protein coding gene Chr10:72121218-72128511 (-)
CBA/J ENSMUSG00210048964
 protein coding gene Chr10:72365540-72372840 (-)
DBA/2J ENSMUSG00185053126
 protein coding gene Chr10:72707842-72715137 (-)
FVB/NJ ENSMUSG00205027255
 protein coding gene Chr10:72400843-72408143 (-)
JF1/MsJ ENSUMUG00000055436
 protein coding gene Chr10:73853987-73861285 (-)
LP/J ENSMUSG00230044848
 protein coding gene Chr10:74477427-74484726 (-)
NOD/ShiLtJ ENSMUSG00190039131
 protein coding gene Chr10:72685358-72692660 (-)
NZO/HlLtJ ENSMUSG00225046079
 protein coding gene Chr10:78773911-78781210 (-)
PWK/PhJ ENSLUMG00010051178
 protein coding gene Chr10:72248525-72255855 (-)
SPRET/EiJ ENSMSPG00010042842
 protein coding gene Chr10:74030471-74038338 (-)
WSB/EiJ ENSIUOG00005050826
 protein coding gene Chr10:72271913-72279191 (-)



Homology
more
  • Human Ortholog
    GSTT3P, glutathione S-transferase theta 3, pseudogene
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GSTT3P, glutathione S-transferase theta 3, pseudogene
  • Links
    NCBI Gene ID: 121853073

  • Chr Location
    22q11.23
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    25
  • cDNA Data
    78
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001665 Ensembl Gene Model | MGI Sequence Detail 7300 C57BL/6J ±  kb
transcript ENSMUST00000001715 Ensembl | MGI Sequence Detail 1880 Not Applicable  
polypeptide ENSMUSP00000001715 Ensembl | MGI Sequence Detail 241 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • EC
    2.5.1.18
  • InterPro Domains
    IPR004046 Glutathione S-transferase, C-terminal
    IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    IPR010987 Glutathione S-transferase, C-terminal-like
    IPR004045 Glutathione S-transferase, N-terminal
    IPR051369 Glutathione S-transferase Theta
    IPR040077 Glutathione S-transferase Theta, C-terminal
    IPR040075 Glutathione S-transferase Theta, N-terminal
    IPR040079 Glutathione transferase family
    IPR036249 Thioredoxin-like superfamily
Molecular
Reagents
less
  • All nucleic 78
    cDNA 78

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:281737 Behrens KA, et al., Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile. PLoS One. 2019;14(11):e0225449
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory