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Cpne7 Gene Detail
Summary
  • Symbol
    Cpne7
  • Name
    copine VII
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142747
    NCBI Gene: 102278
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123844113-123861921 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 72.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    602 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142747
 protein coding gene Chr8:123844054-123861924 (+)
129S1/SvImJ ENSMUSG00200042271
 protein coding gene Chr8:118176932-118195212 (+)
A/J ENSMUSG00195026539
 protein coding gene Chr8:118472623-118490877 (+)
AKR/J ENSMUSG00220036856
 protein coding gene Chr8:118663738-118682215 (+)
BALB/cJ ENSMUSG00180022641
 protein coding gene Chr8:118518637-118536889 (+)
C3H/HeJ ENSMUSG00175028193
 protein coding gene Chr8:118575651-118594127 (+)
C57BL/6NJ ENSMUSG00215022922
 protein coding gene Chr8:118150090-118168363 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031677
 protein coding gene Chr8:114283125-114301666 (+)
CAST/EiJ ENSTCUG00005033251
 protein coding gene Chr8:117896538-117914989 (+)
CBA/J ENSMUSG00210031328
 protein coding gene Chr8:118502519-118520790 (+)
DBA/2J ENSMUSG00185031791
 protein coding gene Chr8:124607461-124625732 (+)
FVB/NJ ENSMUSG00205025422
 protein coding gene Chr8:117468741-117487013 (+)
JF1/MsJ ENSUMUG00000016814
 protein coding gene Chr8:126912329-126930588 (+)
LP/J ENSMUSG00230027892
 protein coding gene Chr8:128228348-128246626 (+)
NOD/ShiLtJ ENSMUSG00190017523
 protein coding gene Chr8:118603003-118621274 (+)
NZO/HlLtJ ENSMUSG00225041458
 protein coding gene Chr8:131607942-131626213 (+)
PWK/PhJ ENSLUMG00010031394
 protein coding gene Chr8:118316630-118335026 (+)
SPRET/EiJ ENSMSPG00010035914
 protein coding gene Chr8:120501602-120519858 (+)
WSB/EiJ ENSIUOG00005026803
 protein coding gene Chr8:119293539-119311829 (+)



Homology
more
  • Human Ortholog
    CPNE7, copine 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPNE7, copine 7
  • Links
    NCBI Gene ID: 27132
    UniProt: Q9UBL6

  • Chr Location
    16q24.3; chr16:89575732-89597247 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 3 alleles in 3 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation show premature aging of the dental pulp in molars.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    682
  • Tissues
    33
  • cDNA Data
    15
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034796 Ensembl Gene Model | MGI Sequence Detail 17809 C57BL/6J ±  kb
    transcript ENSMUST00000037900 Ensembl | MGI Sequence Detail 2398 Not Applicable  
    polypeptide ENSMUSP00000042159 Ensembl | MGI Sequence Detail 557 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 15
      Other 1
      Antibodies 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 7
    • Earliest
      J:86882 Creutz CE, et al., The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans. J Biol Chem. 1998 Jan 16;273(3):1393-402
    • Latest
      J:371487 Tseng CS, et al., A developmental gradient of COUP-TFI expression regulates the relative size of hippocampus dorsal and ventral subregions. PLoS Biol. 2025 Aug;23(8):e3003355
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory