About   Help   FAQ
Zfp518b Gene Detail
Summary
  • Symbol
    Zfp518b
  • Name
    zinc finger protein 518B
  • Synonyms
    6820424L24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140750
    NCBI Gene: 100515
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:38825828-38842120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 20.77 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    520 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140750
 protein coding gene Chr5:38825827-38842169 (-)
129S1/SvImJ ENSMUSG00200029662
 protein coding gene Chr5:34277710-34294053 (-)
A/J ENSMUSG00195027812
 protein coding gene Chr5:33735382-33746030 (-)
AKR/J ENSMUSG00220001928
 protein coding gene Chr5:33756474-33772810 (-)
BALB/cJ ENSMUSG00180020157
 protein coding gene Chr5:33532518-33548854 (-)
C3H/HeJ ENSMUSG00175018546
 protein coding gene Chr5:35516568-35532904 (-)
C57BL/6NJ ENSMUSG00215004925
 protein coding gene Chr5:34277584-34293926 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027183
 protein coding gene Chr5:33510009-33527080 (-)
CAST/EiJ ENSTCUG00005023782
 protein coding gene Chr5:33730402-33746725 (-)
CBA/J ENSMUSG00210004539
 protein coding gene Chr5:34478548-34494884 (-)
DBA/2J ENSMUSG00185016333
 protein coding gene Chr5:36361734-36378077 (-)
FVB/NJ ENSMUSG00205013622
 protein coding gene Chr5:33244193-33260536 (-)
JF1/MsJ ENSUMUG00000000950
 protein coding gene Chr5:40921391-40937954 (-)
LP/J ENSMUSG00230002038
 protein coding gene Chr5:41004721-41021064 (-)
NOD/ShiLtJ ENSMUSG00190003146
 protein coding gene Chr5:33548710-33565053 (-)
NZO/HlLtJ ENSMUSG00225016162
 protein coding gene Chr5:46164133-46180469 (-)
PWK/PhJ ENSLUMG00010022569
 protein coding gene Chr5:33599385-33615730 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005016344
 protein coding gene Chr5:36441196-36457531 (-)



Homology
more
  • Human Ortholog
    ZNF518B, zinc finger protein 518B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF518B, zinc finger protein 518B
  • Links
    NCBI Gene ID: 85460
    UniProt: Q9C0D4

  • Chr Location
    4p16.1; chr4:10439873-10461381 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    23
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    15
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    6 involving Zfp518b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    36 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    77
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100515 NCBI Gene Model | MGI Sequence Detail 16293 C57BL/6J ±  kb
transcript NM_001081144 RefSeq | MGI Sequence Detail 6832 C57BL/6  
polypeptide B2RRE4 UniProt | EBI | MGI Sequence Detail 1077 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140953
References
more
  • Summaries
    All 51
    Diseases 1
    Gene Ontology 3
    Phenotypes 27
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:380308 Ostapcuk V, et al., Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes. Nature. 2018 May;557(7707):739-743
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory