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Iffo2 Gene Detail
Summary
  • Symbol
    Iffo2
  • Name
    intermediate filament family orphan 2
  • Synonyms
    MGC:36549
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140675
    NCBI Gene: 212632
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:139257859-139347693 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 70.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3007 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140675
 protein coding gene Chr4:139257859-139347693 (+)
129S1/SvImJ ENSMUSG00200041544
 protein coding gene Chr4:132672046-132763108 (+)
A/J ENSMUSG00195034974
 protein coding gene Chr4:134015625-134106684 (+)
AKR/J ENSMUSG00220045939
 protein coding gene Chr4:133014569-133105346 (+)
BALB/cJ ENSMUSG00180043454
 protein coding gene Chr4:131654515-131745311 (+)
C3H/HeJ ENSMUSG00175032541
 protein coding gene Chr4:132682614-132773392 (+)
C57BL/6NJ ENSMUSG00215047351
 protein coding gene Chr4:134201107-134292192 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026714
 protein coding gene Chr4:129247161-129293562 (+)
CAST/EiJ ENSTCUG00005012591
 protein coding gene Chr4:133641755-133731589 (+)
CBA/J ENSMUSG00210028431
 protein coding gene Chr4:132306641-132397419 (+)
DBA/2J ENSMUSG00185050025
 protein coding gene Chr4:133820348-133911128 (+)
FVB/NJ ENSMUSG00205047249
 protein coding gene Chr4:132073007-132163122 (+)
JF1/MsJ ENSUMUG00000031385
 protein coding gene Chr4:134513786-134604864 (+)
LP/J ENSMUSG00230036225
 protein coding gene Chr4:137610666-137701695 (+)
NOD/ShiLtJ ENSMUSG00190023491
 protein coding gene Chr4:132074451-132165496 (+)
NZO/HlLtJ ENSMUSG00225007883
 protein coding gene Chr4:143565335-143656390 (+)
PWK/PhJ ENSLUMG00010042564
 protein coding gene Chr4:131500203-131591338 (+)
SPRET/EiJ ENSMSPG00010031936
 protein coding gene Chr4:133559437-133643834 (+)
WSB/EiJ ENSIUOG00005042308
 protein coding gene Chr4:131960780-132051023 (+)



Homology
more
  • Human Ortholog
    IFFO2, intermediate filament family orphan 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFFO2, intermediate filament family orphan 2
  • Links
    NCBI Gene ID: 126917
    UniProt: Q5TF58

  • Chr Location
    1p36.13; chr1:18904280-18956676 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    640
  • Tissues
    5
  • cDNA Data
    56
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 212632 NCBI Gene Model | MGI Sequence Detail 89835 C57BL/6J ±  kb
transcript NM_001205173 RefSeq | MGI Sequence Detail 5763 C57BL/6  
polypeptide Q8R2V2 UniProt | EBI | MGI Sequence Detail 512 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 5
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory