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Cdc123 Gene Detail
Summary
  • Symbol
    Cdc123
  • Name
    cell division cycle 123
  • Synonyms
    G431001I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138811
    NCBI Gene: 98828
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:5799105-5849975 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 3.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1408 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138811
protein coding gene Chr2:5799105-5849988 (-)
129S1/SvImJ ENSMUSG00200028873
protein coding gene Chr2:2658889-2709784 (-)
A/J ENSMUSG00195014909
protein coding gene Chr2:2776362-2827250 (-)
AKR/J ENSMUSG00220005042
protein coding gene Chr2:2767852-2818738 (-)
BALB/cJ ENSMUSG00180029691
protein coding gene Chr2:2865055-2915982 (-)
C3H/HeJ ENSMUSG00175016074
protein coding gene Chr2:2759610-2810502 (-)
C57BL/6NJ ENSMUSG00215008252
protein coding gene Chr2:2890962-2941834 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023152
protein coding gene Chr2:2596192-2647528 (-)
CAST/EiJ ENSTCUG00005004292
protein coding gene Chr2:2750433-2801263 (-)
CBA/J ENSMUSG00210026518
protein coding gene Chr2:2799904-2850816 (-)
DBA/2J ENSMUSG00185012330
protein coding gene Chr2:2759436-2810335 (-)
FVB/NJ ENSMUSG00205028321
protein coding gene Chr2:2734782-2792203 (-)
JF1/MsJ ENSUMUG00000001385
protein coding gene Chr2:2738078-2788200 (-)
LP/J ENSMUSG00230002173
protein coding gene Chr2:4706834-4757718 (-)
NOD/ShiLtJ ENSMUSG00190005443
protein coding gene Chr2:2759989-2816227 (-)
NZO/HlLtJ ENSMUSG00225001581
protein coding gene Chr2:12442396-12493267 (-)
PWK/PhJ ENSLUMG00010027337
protein coding gene Chr2:2793535-2843070 (-)
SPRET/EiJ ENSMSPG00010025573
protein coding gene Chr2:2786396-2837790 (-)
WSB/EiJ ENSIUOG00005021583
protein coding gene Chr2:2771670-2829031 (-)



Homology
more
  • Human Ortholog
    CDC123, cell division cycle 123
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC123, cell division cycle 123
  • Synonyms
    C10orf7, D123
  • Links
    NCBI Gene ID: 8872
    UniProt: O75794

  • Chr Location
    10p14-p13; chr10:12195950-12250595 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039128 Ensembl Gene Model | MGI Sequence Detail 50871 C57BL/6J ±  kb
    transcript ENSMUST00000043864 Ensembl | MGI Sequence Detail 1827 Not Applicable  
    polypeptide ENSMUSP00000043033 Ensembl | MGI Sequence Detail 336 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 140
      cDNA 140

      Microarray probesets 4
    References
    more
    • Summaries
      All 39
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/15/2026
    MGI 6.29
    The Jackson Laboratory