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Gorab Gene Detail
Summary
  • Symbol
    Gorab
  • Name
    golgin, RAB6-interacting
  • Synonyms
    NTKL-BP1, Scyl1bp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138271
    NCBI Gene: 98376
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:163212477-163231238 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 70.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    527 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138271
 protein coding gene Chr1:163212472-163231238 (-)
129S1/SvImJ ENSMUSG00200005548
 protein coding gene Chr1:160682789-160701574 (-)
A/J ENSMUSG00195022354
 protein coding gene Chr1:160022981-160041742 (-)
AKR/J ENSMUSG00220012709
 protein coding gene Chr1:159823102-159841892 (-)
BALB/cJ ENSMUSG00180036886
 protein coding gene Chr1:160264235-160282996 (-)
C3H/HeJ ENSMUSG00175039455
 protein coding gene Chr1:160349518-160368279 (-)
C57BL/6NJ ENSMUSG00215032990
 protein coding gene Chr1:160232788-160251549 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014783
 protein coding gene Chr1:153912625-153931487 (-)
CAST/EiJ ENSTCUG00005020157
 protein coding gene Chr1:158840432-158859194 (-)
CBA/J ENSMUSG00210020979
 protein coding gene Chr1:160228469-160247252 (-)
DBA/2J ENSMUSG00185011380
 protein coding gene Chr1:164484152-164502890 (-)
FVB/NJ ENSMUSG00205007802
 protein coding gene Chr1:159307587-159326373 (-)
JF1/MsJ ENSUMUG00000004153
 protein coding gene Chr1:163634061-163652789 (-)
LP/J ENSMUSG00230023308
 protein coding gene Chr1:164093211-164111994 (-)
NOD/ShiLtJ ENSMUSG00190023899
 protein coding gene Chr1:160068585-160087373 (-)
NZO/HlLtJ ENSMUSG00225002533
 protein coding gene Chr1:167686577-167705364 (-)
PWK/PhJ ENSLUMG00010039688
 protein coding gene Chr1:159029086-159047808 (-)
SPRET/EiJ ENSMSPG00010039598
 protein coding gene Chr1:162488611-162507755 (-)
WSB/EiJ ENSIUOG00005015515
 protein coding gene Chr1:159577159-159595832 (-)



Homology
more
  • Human Ortholog
    GORAB, golgin, RAB6 interacting
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GORAB, golgin, RAB6 interacting
  • Synonyms
    GO, NTKLBP1, SCYL1BP1
  • Links
    NCBI Gene ID: 92344
    UniProt: Q5T7V8

  • Chr Location
    1q24.2; chr1:170531819-170553834 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human GORAB associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null gene trap allele exhibit hunched posture, craniofacial abnormalities, neonatal lethality, respiratory distress, skin edema, decreased hair follicles, fewer dermal condensates and papillae, and impaired formation of primary cilia on dermal condensate cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    5
  • cDNA Data
    31
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040124 Ensembl Gene Model | MGI Sequence Detail 18762 C57BL/6J ±  kb
    transcript ENSMUST00000045138 Ensembl | MGI Sequence Detail 2538 Not Applicable  
    polypeptide ENSMUSP00000036253 Ensembl | MGI Sequence Detail 368 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 32
      cDNA 31
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
    • Latest
      J:345879 Huang X, et al., Single-cell, whole-embryo phenotyping of mammalian developmental disorders. Nature. 2023 Nov;623(7988):772-781
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory