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Lce3c Gene Detail
Summary
  • Symbol
    Lce3c
  • Name
    late cornified envelope 3C
  • Synonyms
    2300007B01Rik, Eig3, Sprrl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135932
    NCBI Gene: 94060
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92851793-92853038 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135932
 protein coding gene Chr3:92851793-92853040 (+)
129S1/SvImJ ENSMUSG00200038880
 protein coding gene Chr3:89639466-89640713 (+)
A/J ENSMUSG00195052656
 protein coding gene Chr3:89648804-89650051 (+)
AKR/J ENSMUSG00220045065
 protein coding gene Chr3:88869978-88871225 (+)
BALB/cJ ENSMUSG00180042325
 protein coding gene Chr3:89819813-89821060 (+)
C3H/HeJ ENSMUSG00175041906
 protein coding gene Chr3:89586620-89587867 (+)
C57BL/6NJ ENSMUSG00215045899
 protein coding gene Chr3:90198304-90199551 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020179
 protein coding gene Chr15:84277176-84277410 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210046747
 protein coding gene Chr3:89701710-89702957 (+)
DBA/2J ENSMUSG00185050155
 protein coding gene Chr3:89904069-89905316 (+)
FVB/NJ ENSMUSG00205044405
 protein coding gene Chr3:88695977-88697224 (+)
JF1/MsJ ENSUMUG00000038251
 protein coding gene Chr3:89478607-89479854 (+)
LP/J ENSMUSG00230043116
 protein coding gene Chr3:91936925-91938172 (+)
NOD/ShiLtJ ENSMUSG00190047105
 protein coding gene Chr3:90051876-90053121 (+)
NZO/HlLtJ ENSMUSG00225009086
 protein coding gene Chr3:94784429-94785676 (+)
PWK/PhJ ENSLUMG00010044263
 protein coding gene Chr3:89534978-89536225 (+)
SPRET/EiJ ENSMSPG00010049189
 protein coding gene Chr3:89983243-89984359 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LCE3A, late cornified envelope 3A
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LCE3A, late cornified envelope 3A
  • Synonyms
    LEP13
  • Links
    NCBI Gene ID: 353142
    UniProt: Q5TA76

  • Chr Location
    1q21.3; chr1:152622834-152623103 (-)  GRCh38
  • Human Ortholog
    LCE3B, late cornified envelope 3B
  • Synonyms
    LEP14
  • Links
    NCBI Gene ID: 353143
    UniProt: Q5TA77

  • Chr Location
    1q21.3; chr1:152613811-152614098 (+)  GRCh38
  • Human Ortholog
    LCE3C, late cornified envelope 3C
  • Synonyms
    LEP15, SPRL3A
  • Links
    NCBI Gene ID: 353144
    UniProt: Q5T5A8

  • Chr Location
    1q21.3; chr1:152600234-152601086 (+)  GRCh38
  • Human Ortholog
    LCE3D, late cornified envelope 3D
  • Synonyms
    LEP16, SPRL6A, SPRL6B
  • Links
    NCBI Gene ID: 84648
    UniProt: Q9BYE3

  • Chr Location
    1q21.3; chr1:152579381-152580516 (-)  GRCh38
  • Human Ortholog
    LCE3E, late cornified envelope 3E
  • Synonyms
    LEP17
  • Links
    NCBI Gene ID: 353145
    UniProt: Q5T5B0

  • Chr Location
    1q21.3; chr1:152565654-152566780 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Lce3c
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    612
  • Tissues
    7
  • cDNA Data
    8
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94060 NCBI Gene Model | MGI Sequence Detail 1246 C57BL/6J ±  kb
transcript NM_033175 RefSeq | MGI Sequence Detail 565 C57BL/6  
polypeptide NP_149410 RefSeq | MGI Sequence Detail 98 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR028205 Late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916717, MGI:2139932
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory