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Slc43a1 Gene Detail
Summary
  • Symbol
    Slc43a1
  • Name
    solute carrier family 43, member 1
  • Synonyms
    2610016F07Rik, Lat3, PB39, Pov1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931352
    NCBI Gene: 72401
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:84669196-84693930 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 49.45 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    587 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931352
 protein coding gene Chr2:84669194-84693938 (+)
129S1/SvImJ ENSMUSG00200053000
 protein coding gene Chr2:81685716-81710461 (+)
A/J ENSMUSG00195050153
 protein coding gene Chr2:81798481-81823224 (+)
AKR/J ENSMUSG00220050857
 protein coding gene Chr2:81677208-81701939 (+)
BALB/cJ ENSMUSG00180054652
 protein coding gene Chr2:81726316-81751056 (+)
C3H/HeJ ENSMUSG00175051629
 protein coding gene Chr2:81865895-81890624 (+)
C57BL/6NJ ENSMUSG00215052479
 protein coding gene Chr2:81770843-81795587 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023733
 protein coding gene Chr2:79049062-79074300 (+)
CAST/EiJ ENSTCUG00005050496
 protein coding gene Chr2:81216754-81241532 (+)
CBA/J ENSMUSG00210027300
 protein coding gene Chr2:81893817-81918536 (+)
DBA/2J ENSMUSG00185056647
 protein coding gene Chr2:81722557-81747296 (+)
FVB/NJ ENSMUSG00205047493
 protein coding gene Chr2:81109504-81134276 (+)
JF1/MsJ ENSUMUG00000004370
 protein coding gene Chr2:81647495-81672417 (+)
LP/J ENSMUSG00230040179
 protein coding gene Chr2:83473643-83498376 (+)
NOD/ShiLtJ ENSMUSG00190043134
 protein coding gene Chr2:81763127-81787869 (+)
NZO/HlLtJ ENSMUSG00225001819
 protein coding gene Chr2:91358269-91383014 (+)
PWK/PhJ ENSLUMG00010045169
 protein coding gene Chr2:81663787-81689752 (+)
SPRET/EiJ ENSMSPG00010052015
 protein coding gene Chr2:83564736-83589200 (+)
WSB/EiJ ENSIUOG00005053238
 protein coding gene Chr2:81702636-81727402 (+)



Homology
more
  • Human Ortholog
    SLC43A1, solute carrier family 43 member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC43A1, solute carrier family 43 member 1
  • Synonyms
    LAT3, PB39, POV1, R00504
  • Links
    NCBI Gene ID: 8501
    UniProt: O75387

  • Chr Location
    11q12.1; chr11:57484064-57515780 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    8
  • Targeted
    5
  • Genomic Mutations
    3 involving Slc43a1
  • Find Mice (IMSR)
    25 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    101
  • cDNA Data
    12
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72401 NCBI Gene Model | MGI Sequence Detail 24735 C57BL/6J ±  kb
transcript NM_001081349 RefSeq | MGI Sequence Detail 2539 C57BL/6  
polypeptide Q8BSM7 UniProt | EBI | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 12
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919651, MGI:2138819
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:49540 Cole KA, et al., cDNA sequencing and analysis of POV1 (PB39): a novel gene up-regulated in prostate cancer. Genomics. 1998 Jul 15;51(2):282-7
  • Latest
    J:353480 Huang S, et al., Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis. Nat Commun. 2024 Aug 15;15(1):7019
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory