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Bcam Gene Detail
Summary
  • Symbol
    Bcam
  • Name
    basal cell adhesion molecule
  • Synonyms
    1200005K12Rik, B-CAM, Lu
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929940
    NCBI Gene: 57278
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:19490063-19504457 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929940
 protein coding gene Chr7:19490056-19504941 (-)
129S1/SvImJ ENSMUSG00200038208
 protein coding gene Chr7:12687933-12702538 (-)
A/J ENSMUSG00195050385
 protein coding gene Chr7:13127424-13142309 (-)
AKR/J ENSMUSG00220025868
 protein coding gene Chr7:11459526-11474419 (-)
BALB/cJ ENSMUSG00180053105
 protein coding gene Chr7:12983752-12998637 (-)
C3H/HeJ ENSMUSG00175040564
 protein coding gene Chr7:13570481-13585087 (-)
C57BL/6NJ ENSMUSG00215054713
 protein coding gene Chr7:10705380-10720267 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029308
 protein coding gene Chr7:19054597-19070084 (-)
CAST/EiJ ENSTCUG00005049778
 protein coding gene Chr7:13592185-13606941 (-)
CBA/J ENSMUSG00210051210
 protein coding gene Chr7:12797019-12811620 (-)
DBA/2J ENSMUSG00185050819
 protein coding gene Chr7:16240429-16255644 (-)
FVB/NJ ENSMUSG00205050026
 protein coding gene Chr7:13178803-13193695 (-)
JF1/MsJ ENSUMUG00000024238
 protein coding gene Chr7:19554455-19569055 (-)
LP/J ENSMUSG00230052575
 protein coding gene Chr7:20529462-20543776 (-)
NOD/ShiLtJ ENSMUSG00190037676
 protein coding gene Chr7:9453331-9467936 (-)
NZO/HlLtJ ENSMUSG00225052196
 protein coding gene Chr7:17822515-17837406 (-)
PWK/PhJ ENSLUMG00010043274
 protein coding gene Chr7:2411184-2425939 (-)
SPRET/EiJ ENSMSPG00010043023
 protein coding gene Chr7:12529533-12544128 (-)
WSB/EiJ ENSIUOG00005052633
 protein coding gene Chr7:19069589-19084460 (+)



Homology
more
  • Human Ortholog
    BCAM, basal cell adhesion molecule (Lutheran blood group)
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCAM, basal cell adhesion molecule (Lutheran blood group)
  • Synonyms
    AU, B-CAM, CD239, F8/G253, LU, MSK19
  • Links
    NCBI Gene ID: 4059
    UniProt: P50895

  • Chr Location
    19q13.32; chr19:44809059-44821421 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotypes from multigenic genotypes
    15 phenotype references
A gene trap insertion into an intron of this gene results in no obvious phenotype. Mice homozygous for a null allele exhibit glomeruli abnormalities and increased thickness and disorganization of intestinal smooth muscle.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • Tissues
    23
  • cDNA Data
    104
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57278 NCBI Gene Model | MGI Sequence Detail 14395 C57BL/6J ±  kb
transcript NM_020486 RefSeq | MGI Sequence Detail 2407 Not Specified  
polypeptide Q9R069 UniProt | EBI | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    cDNA 104
    Primer pair 2
    Antibodies 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:1918955
References
more
  • Summaries
    All 52
    Developmental Gene Expression 10
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:61456 Rahuel C, et al., Characterization of a mouse liminin receptor gene homologous to the human blood group Lutheran gene. Immunogenetics. 1999 Dec;50(5-6):271-7
  • Latest
    J:372263 Jasmine, et al., Single cell map of the adult female mouse urethra reveals epithelial and stromal macrophages with distinct functional identities. Mucosal Immunol. 2025 Sep 2;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory