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Nudt3 Gene Detail
Summary
  • Symbol
    Nudt3
  • Name
    nudix hydrolase 3
  • Synonyms
    1110011B09Rik, diphosphoinositol polyphosphate phosphohydrolase, Dipp, nudix (nucleoside diphosphate linked moiety X)-type motif 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928484
    NCBI Gene: 56409
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:27798356-27842426 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    543 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928484
protein coding gene Chr17:27798356-27842469 (-)
129S1/SvImJ ENSMUSG00200053740
protein coding gene Chr17:23460362-23504743 (-)
A/J ENSMUSG00195054295
protein coding gene Chr17:24274982-24318298 (-)
AKR/J ENSMUSG00220048879
protein coding gene Chr17:23322616-23365939 (-)
BALB/cJ ENSMUSG00180049307
protein coding gene Chr17:23757206-23801591 (-)
C3H/HeJ ENSMUSG00175048201
protein coding gene Chr17:23311119-23354437 (-)
C57BL/6NJ ENSMUSG00215052094
protein coding gene Chr17:23308953-23353083 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021303
protein coding gene Chr17:23426706-23473695 (-)
CAST/EiJ ENSTCUG00005048246
protein coding gene Chr17:24033824-24087217 (-)
CBA/J ENSMUSG00210045886
protein coding gene Chr17:23149564-23192879 (-)
DBA/2J ENSMUSG00185050995
protein coding gene Chr17:25363181-25406499 (-)
FVB/NJ ENSMUSG00205023716
protein coding gene Chr17:23625980-23669300 (-)
JF1/MsJ ENSUMUG00000029133
protein coding gene Chr17:24817361-24864403 (-)
LP/J ENSMUSG00230054992
protein coding gene Chr17:26886223-26930600 (-)
NOD/ShiLtJ ENSMUSG00190049269
protein coding gene Chr17:23256439-23300558 (-)
NZO/HlLtJ ENSMUSG00225051590
protein coding gene Chr17:28850362-28894479 (-)
PWK/PhJ ENSLUMG00010053279
protein coding gene Chr17:22738101-22785216 (-)
SPRET/EiJ ENSMSPG00010045999
protein coding gene Chr17:24040471-24086117 (-)
WSB/EiJ ENSIUOG00005049519
protein coding gene Chr17:24014477-24061253 (-)



Homology
more
  • Human Ortholog
    NUDT3, nudix hydrolase 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT3, nudix hydrolase 3
  • Synonyms
    DIPP, DIPP-1, DIPP1
  • Links
    NCBI Gene ID: 11165
    UniProt: O95989

  • Chr Location
    6p21.31; chr6:34279679-34392677 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56409 NCBI Gene Model | MGI Sequence Detail 44071 C57BL/6J ±  kb
transcript NM_001291046 RefSeq | MGI Sequence Detail 2188 C57BL/6  
polypeptide Q9JI46 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000011494 diphosphoinositol polyphosphate phosphohydrolase 1
  • GlyGen
    Q9JI46 5 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (4 sites)
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915745, MGI:2146786
References
more
  • Summaries
    All 44
    Gene Ontology 12
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory