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B4galt6 Gene Detail
Summary
  • Symbol
    B4galt6
  • Name
    UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928380
    NCBI Gene: 56386
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:20817656-20879461 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 11.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1851 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928380
 protein coding gene Chr18:20817656-20879461 (-)
129S1/SvImJ ENSMUSG00200019482
 protein coding gene Chr18:17820798-17882612 (-)
A/J ENSMUSG00195002049
 protein coding gene Chr18:17970364-18032181 (-)
AKR/J ENSMUSG00220011414
 protein coding gene Chr18:17972405-18034247 (-)
BALB/cJ ENSMUSG00180003979
 protein coding gene Chr18:18431627-18493440 (-)
C3H/HeJ ENSMUSG00175004351
 protein coding gene Chr18:17918843-17980656 (-)
C57BL/6NJ ENSMUSG00215003481
 protein coding gene Chr18:17670600-17732413 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022031
 protein coding gene Chr18:16906676-16968582 (-)
CAST/EiJ ENSTCUG00005014172
 protein coding gene Chr18:17711763-17774661 (-)
CBA/J ENSMUSG00210019979
 protein coding gene Chr18:17983215-18045036 (-)
DBA/2J ENSMUSG00185007511
 protein coding gene Chr18:17940500-18002320 (-)
FVB/NJ ENSMUSG00205015296
 protein coding gene Chr18:17672395-17734223 (-)
JF1/MsJ ENSUMUG00000022920
 protein coding gene Chr18:17998833-18060615 (-)
LP/J ENSMUSG00230010994
 protein coding gene Chr18:20016996-20078803 (-)
NOD/ShiLtJ ENSMUSG00190016891
 protein coding gene Chr18:17755167-17816988 (-)
NZO/HlLtJ ENSMUSG00225027853
 protein coding gene Chr18:19944359-20006164 (-)
PWK/PhJ ENSLUMG00010015548
 protein coding gene Chr18:18188852-18250874 (-)
SPRET/EiJ ENSMSPG00010004761
 protein coding gene Chr18:18077620-18136782 (-)
WSB/EiJ ENSIUOG00005019028
 protein coding gene Chr18:17770798-17832698 (-)



Homology
more
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
  • Synonyms
    B4Gal-T6, beta4Gal-T6
  • Links
    NCBI Gene ID: 9331
    UniProt: Q9UBX8

  • Chr Location
    18q12.1; chr18:31621911-31724641 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display a normal phenotype with reduced lactosylceramide synthase in MEFs.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    28
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    882
  • Tissues
    155
  • cDNA Data
    16
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56386 NCBI Gene Model | MGI Sequence Detail 61806 C57BL/6J ±  kb
transcript NM_019737 RefSeq | MGI Sequence Detail 5808 C57BL/6  
polypeptide Q9WVK5 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2147179, MGI:2147314
References
more
  • Summaries
    All 51
    Developmental Gene Expression 7
    Gene Ontology 12
    Phenotypes 14
  • Earliest
    J:47946 Nomura T, et al., Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain. J Biol Chem. 1998 May 29;273(22):13570-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory