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Tmem131 Gene Detail
Summary
  • Symbol
    Tmem131
  • Name
    transmembrane protein 131
  • Synonyms
    2610524E03Rik, CC28, D1Bwg0491e, mKIAA0257, Neg, Rw1, YR-23
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927110
    NCBI Gene: 56030
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36831270-36978714 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3792 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927110
 protein coding gene Chr1:36831270-36982747 (-)
129S1/SvImJ ENSMUSG00200003982
 protein coding gene Chr1:34420259-34567634 (-)
A/J ENSMUSG00195039782
 protein coding gene Chr1:34047869-34194319 (-)
AKR/J ENSMUSG00220008758
 protein coding gene Chr1:34068378-34214734 (-)
BALB/cJ ENSMUSG00180011210
 protein coding gene Chr1:34165594-34312976 (-)
C3H/HeJ ENSMUSG00175001020
 protein coding gene Chr1:34051953-34198423 (-)
C57BL/6NJ ENSMUSG00215015778
 protein coding gene Chr1:34142557-34289931 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014046
 protein coding gene Chr1:31443017-31596331 (-)
CAST/EiJ ENSTCUG00005002716
 protein coding gene Chr1:34224100-34370141 (-)
CBA/J ENSMUSG00210005846
 protein coding gene Chr1:33894185-34040536 (-)
DBA/2J ENSMUSG00185009919
 protein coding gene Chr1:34978321-35125928 (-)
FVB/NJ ENSMUSG00205030805
 protein coding gene Chr1:34071338-34217756 (-)
JF1/MsJ ENSUMUG00000006694
 protein coding gene Chr1:34185766-34333165 (-)
LP/J ENSMUSG00230023789
 protein coding gene Chr1:35041063-35188431 (-)
NOD/ShiLtJ ENSMUSG00190029182
 protein coding gene Chr1:34082732-34229164 (-)
NZO/HlLtJ ENSMUSG00225013876
 protein coding gene Chr1:38282270-38428614 (-)
PWK/PhJ ENSLUMG00010035257
 protein coding gene Chr1:33723555-33871399 (-)
SPRET/EiJ ENSMSPG00010023360
 protein coding gene Chr1:35195755-35347519 (-)
WSB/EiJ ENSIUOG00005037384
 protein coding gene Chr1:34031234-34179557 (-)



Homology
more
  • Human Ortholog
    TMEM131, transmembrane protein 131
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM131, transmembrane protein 131
  • Synonyms
    CC28, PRO1048, RW1, YR-23
  • Links
    NCBI Gene ID: 23505
    UniProt: Q92545

  • Chr Location
    2q11.2; chr2:97756333-97996226 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    603
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56030 NCBI Gene Model | MGI Sequence Detail 147445 C57BL/6J ±  kb
    transcript NM_018872 RefSeq | MGI Sequence Detail 6563 C57BL/6  
    polypeptide O70472 UniProt | EBI | MGI Sequence Detail 1877 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 12
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-34271, MGI:106577, MGI:1917288
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 16
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory