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Impg1 Gene Detail
Summary
  • Symbol
    Impg1
  • Name
    interphotoreceptor matrix proteoglycan 1
  • Synonyms
    A930015H12Rik, IMP150, SPACR
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926876
    NCBI Gene: 63859
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:80220612-80347534 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 43.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3956 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926876
 protein coding gene Chr9:80215467-80347707 (-)
129S1/SvImJ ENSMUSG00200018506
 protein coding gene Chr9:77323461-77455510 (-)
A/J ENSMUSG00195010093
 protein coding gene Chr9:77145986-77280993 (-)
AKR/J ENSMUSG00220014490
 protein coding gene Chr9:77245758-77373555 (-)
BALB/cJ ENSMUSG00180017084
 protein coding gene Chr9:77256618-77388669 (-)
C3H/HeJ ENSMUSG00175010637
 protein coding gene Chr9:77314885-77446935 (-)
C57BL/6NJ ENSMUSG00215012777
 protein coding gene Chr9:77217088-77345183 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032479
 protein coding gene Chr9:77244530-77379270 (-)
CAST/EiJ ENSTCUG00005008908
 protein coding gene Chr9:76892343-77027816 (-)
CBA/J ENSMUSG00210013125
 protein coding gene Chr9:77346231-77478308 (-)
DBA/2J ENSMUSG00185007262
 protein coding gene Chr9:77374674-77506713 (-)
FVB/NJ ENSMUSG00205025993
 protein coding gene Chr9:77523920-77655982 (-)
JF1/MsJ ENSUMUG00000028037
 protein coding gene Chr9:77256553-77384429 (-)
LP/J ENSMUSG00230024640
 protein coding gene Chr9:77472371-77604386 (-)
NOD/ShiLtJ ENSMUSG00190030850
 protein coding gene Chr9:77451378-77579150 (-)
NZO/HlLtJ ENSMUSG00225025383
 protein coding gene Chr9:77672502-77804541 (-)
PWK/PhJ ENSLUMG00010015724
 protein coding gene Chr9:77200633-77334673 (-)
SPRET/EiJ ENSMSPG00010003927
 protein coding gene Chr9:78508494-78644677 (-)
WSB/EiJ ENSIUOG00005025278
 protein coding gene Chr9:76808315-76941645 (-)



Homology
more
  • Human Ortholog
    IMPG1, interphotoreceptor matrix proteoglycan 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IMPG1, interphotoreceptor matrix proteoglycan 1
  • Synonyms
    GP147, IPM150, RP91, SPACR, VMD4
  • Links
    NCBI Gene ID: 3617
    UniProt: Q17R60

  • Chr Location
    6q14.1; chr6:75921114-76072678 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human IMPG1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display minor retinal abnormalities but normal scotopic and photopic responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032343 Ensembl Gene Model | MGI Sequence Detail 126923 C57BL/6J ±  kb
transcript ENSMUST00000113250 Ensembl | MGI Sequence Detail 2965 Not Applicable  
polypeptide ENSMUSP00000108876 Ensembl | MGI Sequence Detail 798 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925209
References
more
  • Summaries
    All 34
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:380111 Kuehn MH, et al., Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan. Matrix Biol. 1999 Oct;18(5):509-18
  • Latest
    J:346749 Williams BN, et al., Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations. Hum Mol Genet. 2024 Feb 18;33(5):448-464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory