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P2ry10 Gene Detail
Summary
  • Symbol
    P2ry10
  • Name
    purinergic receptor P2Y, G-protein coupled 10
  • Synonyms
    5830408N17Rik, P2Y10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926076
    NCBI Gene: 78826
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:106132098-106148580 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 47.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    476 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926076
 protein coding gene ChrX:106132098-106148580 (+)
129S1/SvImJ ENSMUSG00200037765
 protein coding gene ChrX:87921773-87938262 (+)
A/J ENSMUSG00195037935
 protein coding gene ChrX:91645981-91662463 (+)
AKR/J ENSMUSG00220035247
 protein coding gene ChrX:86375638-86392123 (+)
BALB/cJ ENSMUSG00180039137
 protein coding gene ChrX:88312062-88328544 (+)
C3H/HeJ ENSMUSG00175039977
 protein coding gene ChrX:91887879-91904361 (+)
C57BL/6NJ ENSMUSG00215044917
 protein coding gene ChrX:88541379-88557861 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033335
 protein coding gene ChrX:101066327-101083194 (+)
CAST/EiJ ENSTCUG00005040217
 protein coding gene ChrX:89340482-89357014 (+)
CBA/J ENSMUSG00210039966
 protein coding gene ChrX:88781510-88797992 (+)
DBA/2J ENSMUSG00185042623
 protein coding gene ChrX:101267015-101283504 (+)
FVB/NJ ENSMUSG00205032215
 protein coding gene ChrX:87851212-87867692 (+)
JF1/MsJ ENSUMUG00000015829
 protein coding gene ChrX:121843081-121859661 (+)
LP/J ENSMUSG00230041559
 protein coding gene ChrX:107919119-107935608 (+)
NOD/ShiLtJ ENSMUSG00190037626
 protein coding gene ChrX:87992157-88008639 (+)
NZO/HlLtJ ENSMUSG00225039636
 protein coding gene ChrX:113056896-113073362 (+)
PWK/PhJ ENSLUMG00010033890
 protein coding gene ChrX:87099112-87115843 (+)
SPRET/EiJ ENSMSPG00010039150
 protein coding gene ChrX:91410894-91427421 (+)
WSB/EiJ ENSIUOG00005040846
 protein coding gene ChrX:88501244-88517742 (+)



Homology
more
  • Human Ortholog
    P2RY10, P2Y receptor family member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    P2RY10, P2Y receptor family member 10
  • Synonyms
    LPS2, LYPSR2, P2Y10
  • Links
    NCBI Gene ID: 27334
    UniProt: O00398

  • Chr Location
    Xq21.1; chrX:78945332-78963727 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    1
  • cDNA Data
    42
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78826 NCBI Gene Model | MGI Sequence Detail 16483 C57BL/6J ±  kb
transcript NM_172435 RefSeq | MGI Sequence Detail 2849 C57BL/6  
polypeptide Q8BFU7 UniProt | EBI | MGI Sequence Detail 328 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:58852 Rao S, et al., The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor. J Biol Chem. 1999 Nov 26;274(48):34245-52
  • Latest
    J:367721 Uwamizu A, et al., Autocrine/paracrine lysophosphatidylserine signaling suppresses B cell aggregation and tertiary lymphoid structure formation. iScience. 2025 May 16;28(5):112420
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory