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Bola3 Gene Detail
Summary
  • Symbol
    Bola3
  • Name
    bolA family member 3
  • Synonyms
    1810056O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925903
    NCBI Gene: 78653
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83326129-83337118 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    440 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925903
 protein coding gene Chr6:83326129-83337118 (+)
129S1/SvImJ ENSMUSG00200011219
 protein coding gene Chr6:80295021-80306011 (+)
A/J ENSMUSG00195011942
 protein coding gene Chr6:79971851-79982841 (+)
AKR/J ENSMUSG00220001918
 protein coding gene Chr6:78916191-78927120 (+)
BALB/cJ ENSMUSG00180009779
 protein coding gene Chr6:80347873-80358863 (+)
C3H/HeJ ENSMUSG00175031300
 protein coding gene Chr6:97050746-97061735 (-)
C57BL/6NJ ENSMUSG00215008495
 protein coding gene Chr6:80345777-80356767 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028555
 protein coding gene Chr6:79494158-79505629 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210010604
 protein coding gene Chr6:80164128-80175117 (+)
DBA/2J ENSMUSG00185041012
 protein coding gene Chr6:80711209-80722198 (+)
FVB/NJ ENSMUSG00205016386
 protein coding gene Chr6:79389528-79400518 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230050001
 protein coding gene Chr6:81852272-81863262 (+)
NOD/ShiLtJ ENSMUSG00190001249
 protein coding gene Chr6:79792654-79803644 (+)
NZO/HlLtJ ENSMUSG00225018048
 protein coding gene Chr6:83764106-83775195 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    BOLA3, bolA family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BOLA3, bolA family member 3
  • Synonyms
    MMDS2
  • Links
    NCBI Gene ID: 388962
    UniProt: Q53S33

  • Chr Location
    2p13.1; chr2:74135397-74147977 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human BOLA3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice in which the gene is deleted in fat tissue, show impaired glucose tolerance, impaired norepinephrine-induced brown adipose tissue thermogenesis, increased weight gain at thermoneutral temperature and decreased brown adipose tissue glucose uptake
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    47
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 78653 NCBI Gene Model | MGI Sequence Detail 10990 C57BL/6J ±  kb
    transcript NM_001363773 RefSeq | MGI Sequence Detail 2365 Not Specified  
    polypeptide Q8CEI1 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 48
      cDNA 48

      Microarray probesets 5
    References
    more
    • Summaries
      All 42
      Gene Ontology 6
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory