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Rbsn Gene Detail
Summary
  • Symbol
    Rbsn
  • Name
    rabenosyn, RAB effector
  • Synonyms
    5330426D11Rik, Rabenosyn-5, Zfyve20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925537
    NCBI Gene: 78287
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:92163693-92191874 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 41.03 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    782 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925537
 protein coding gene Chr6:92163693-92191906 (-)
129S1/SvImJ ENSMUSG00200042307
 protein coding gene Chr6:89117669-89149994 (-)
A/J ENSMUSG00195039018
 protein coding gene Chr6:88837138-88869459 (-)
AKR/J ENSMUSG00220030172
 protein coding gene Chr6:87748274-87773465 (-)
BALB/cJ ENSMUSG00180016745
 protein coding gene Chr6:89202319-89234641 (-)
C3H/HeJ ENSMUSG00175024162
 protein coding gene Chr6:88207821-88233010 (+)
C57BL/6NJ ENSMUSG00215026473
 protein coding gene Chr6:89206524-89231713 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028663
 protein coding gene Chr6:88229412-88259106 (-)
CAST/EiJ ENSTCUG00005016828
 protein coding gene Chr6:89319919-89345155 (-)
CBA/J ENSMUSG00210041982
 protein coding gene Chr6:88991167-89016356 (-)
DBA/2J ENSMUSG00185042764
 protein coding gene Chr6:89535576-89567901 (-)
FVB/NJ ENSMUSG00205027575
 protein coding gene Chr6:88189085-88214289 (-)
JF1/MsJ ENSUMUG00000040725
 protein coding gene Chr6:88476423-88501624 (-)
LP/J ENSMUSG00230050043
 protein coding gene Chr6:90675407-90707732 (-)
NOD/ShiLtJ ENSMUSG00190036565
 protein coding gene Chr6:88601779-88626980 (-)
NZO/HlLtJ ENSMUSG00225039315
 protein coding gene Chr6:92678267-92710592 (-)
PWK/PhJ ENSLUMG00010028057
 protein coding gene Chr6:87896070-87921127 (-)
SPRET/EiJ ENSMSPG00010038205
 protein coding gene Chr6:90173066-90202167 (-)
WSB/EiJ ENSIUOG00005032133
 protein coding gene Chr6:89596227-89621415 (-)



Homology
more
  • Human Ortholog
    RBSN, rabenosyn, RAB effector
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBSN, rabenosyn, RAB effector
  • Synonyms
    KAREVS, MFANDO, Rabenosyn-5, ZFYVE20
  • Links
    NCBI Gene ID: 64145
    UniProt: Q9H1K0

  • Chr Location
    3p25.1; chr3:15068571-15099163 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RBSN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • Tissues
    34
  • cDNA Data
    94
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78287 NCBI Gene Model | MGI Sequence Detail 28182 C57BL/6J ±  kb
transcript NM_030081 RefSeq | MGI Sequence Detail 5301 C57BL/6  
polypeptide Q80Y56 UniProt | EBI | MGI Sequence Detail 783 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 95

    Microarray probesets 7
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory