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Cox7b2 Gene Detail
Summary
  • Symbol
    Cox7b2
  • Name
    cytochrome c oxidase subunit 7B2
  • Synonyms
    4930503B16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925424
    NCBI Gene: 78174
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:71600167-71705548 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 37.98 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2406 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925424
 protein coding gene Chr5:71600166-71705548 (-)
129S1/SvImJ ENSMUSG00200033516
 protein coding gene Chr5:67256823-67362187 (-)
A/J ENSMUSG00195030364
 protein coding gene Chr5:66581042-66686429 (-)
AKR/J ENSMUSG00220004313
 protein coding gene Chr5:66691137-66796525 (-)
BALB/cJ ENSMUSG00180020534
 protein coding gene Chr5:66341828-66439163 (-)
C3H/HeJ ENSMUSG00175024227
 protein coding gene Chr5:68402294-68507668 (-)
C57BL/6NJ ENSMUSG00215004800
 protein coding gene Chr5:67157470-67262871 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027278
 protein coding gene Chr5:64420787-64522735 (-)
CAST/EiJ ENSTCUG00005031264
 protein coding gene Chr5:66171766-66276520 (-)
CBA/J ENSMUSG00210023129
 protein coding gene Chr5:67340539-67445922 (-)
DBA/2J ENSMUSG00185005262
 protein coding gene Chr5:69170372-69275546 (-)
FVB/NJ ENSMUSG00205018211
 protein coding gene Chr5:66137054-66242444 (-)
JF1/MsJ ENSUMUG00000004394
 protein coding gene Chr5:73635703-73740675 (-)
LP/J ENSMUSG00230019114
 protein coding gene Chr5:73831250-73936625 (-)
NOD/ShiLtJ ENSMUSG00190004131
 protein coding gene Chr5:66266500-66371864 (-)
NZO/HlLtJ ENSMUSG00225009050
 protein coding gene Chr5:78909460-79006838 (-)
PWK/PhJ ENSLUMG00010013981
 protein coding gene Chr5:66224166-66329105 (-)
SPRET/EiJ ENSMSPG00010028542
 protein coding gene Chr5:68150852-68251840 (-)
WSB/EiJ ENSIUOG00005018084
 protein coding gene Chr5:69102983-69200273 (-)



Homology
more
  • Human Ortholog
    COX7B2, cytochrome c oxidase subunit 7B2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX7B2, cytochrome c oxidase subunit 7B2
  • Links
    NCBI Gene ID: 170712
    UniProt: Q8TF08

  • Chr Location
    4p12; chr4:46734827-46909245 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired sperm fertilization, asthenozoospermia, tetratozoospermia, and disorganized midpiece mitochondria.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    701
  • Tissues
    104
  • cDNA Data
    15
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000049387 Ensembl Gene Model | MGI Sequence Detail 105382 C57BL/6J ±  kb
    transcript ENSMUST00000050129 Ensembl | MGI Sequence Detail 542 Not Applicable  
    polypeptide ENSMUSP00000060890 Ensembl | MGI Sequence Detail 82 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000005790 cytochrome c oxidase subunit 7B2, mitochondrial
      (term hierarchy)
    • InterPro Domains
      IPR008433 Cytochrome C oxidase, subunit VIIB
      IPR023272 Cytochrome C oxidase, subunit VIIB domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 15
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 19
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:308859 Akter MS, et al., CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice. Sci Rep. 2021 Jul 29;11(1):15438
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory