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Hyal4 Gene Detail
Summary
  • Symbol
    Hyal4
  • Name
    hyaluronoglucosaminidase 4
  • Synonyms
    4632428M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924292
    NCBI Gene: 77042
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:24748366-24766518 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 11.28 cM, cytoband A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    705 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924292
 protein coding gene Chr6:24748328-24767661 (+)
129S1/SvImJ ENSMUSG00200035049
 protein coding gene Chr6:21800449-21819788 (+)
A/J ENSMUSG00195007760
 protein coding gene Chr6:21742178-21761530 (+)
AKR/J ENSMUSG00220003109
 protein coding gene Chr6:21312334-21331684 (+)
BALB/cJ ENSMUSG00180022062
 protein coding gene Chr6:21873190-21892539 (+)
C3H/HeJ ENSMUSG00175017297
 protein coding gene Chr6:21731550-21750885 (+)
C57BL/6NJ ENSMUSG00215022695
 protein coding gene Chr6:21816870-21836211 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028147
 protein coding gene Chr6:19837821-19856364 (+)
CAST/EiJ ENSTCUG00005024316
 protein coding gene Chr6:21421491-21440914 (+)
CBA/J ENSMUSG00210003405
 protein coding gene Chr6:21749876-21769225 (+)
DBA/2J ENSMUSG00185020599
 protein coding gene Chr6:21853008-21872359 (+)
FVB/NJ ENSMUSG00205022703
 protein coding gene Chr6:21822742-21842078 (+)
JF1/MsJ ENSUMUG00000020789
 protein coding gene Chr6:21585046-21604253 (+)
LP/J ENSMUSG00230029503
 protein coding gene Chr6:22817396-22836733 (+)
NOD/ShiLtJ ENSMUSG00190023477
 protein coding gene Chr6:21604564-21623895 (+)
NZO/HlLtJ ENSMUSG00225014242
 protein coding gene Chr6:24757807-24777160 (+)
PWK/PhJ ENSLUMG00010022016
 protein coding gene Chr6:21354562-21380669 (+)
SPRET/EiJ ENSMSPG00010021534
 protein coding gene Chr6:21694709-21709575 (+)
WSB/EiJ ENSIUOG00005029899
 protein coding gene Chr6:21873328-21892669 (+)



Homology
more
  • Human Ortholog
    HYAL4, hyaluronidase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HYAL4, hyaluronidase 4
  • Synonyms
    CSHY, HYAL-4
  • Links
    NCBI Gene ID: 23553
    UniProt: Q2M3T9

  • Chr Location
    7q31.32; chr7:123763708-123877481 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    115
  • cDNA Data
    7
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77042 NCBI Gene Model | MGI Sequence Detail 18153 C57BL/6J ±  kb
    transcript NM_029848 RefSeq | MGI Sequence Detail 2088 Not Specified  
    polypeptide Q05A56 UniProt | EBI | MGI Sequence Detail 481 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 7
      Primer pair 5

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory