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Tmem234 Gene Detail
Summary
  • Symbol
    Tmem234
  • Name
    transmembrane protein 234
  • Synonyms
    1500002D11Rik, 2510006D16Rik, 4933407D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924049
    NCBI Gene: 76799
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129494449-129502326 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.26 cM, cytoband D2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    92 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924049
 protein coding gene Chr4:129494449-129517852 (+)
129S1/SvImJ ENSMUSG00200020089
 protein coding gene Chr4:122933323-122956144 (+)
A/J ENSMUSG00195036796
 protein coding gene Chr4:124269128-124291950 (+)
AKR/J ENSMUSG00220045987
 protein coding gene Chr4:123260661-123283482 (+)
BALB/cJ ENSMUSG00180047928
 protein coding gene Chr4:121902822-121925643 (+)
C3H/HeJ ENSMUSG00175044259
 protein coding gene Chr4:122915432-122938253 (+)
C57BL/6NJ ENSMUSG00215051387
 protein coding gene Chr4:124418708-124442099 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026527
 protein coding gene Chr4:119407628-119415863 (+)
CAST/EiJ ENSTCUG00005043257
 protein coding gene Chr4:123799091-123822613 (+)
CBA/J ENSMUSG00210053594
 protein coding gene Chr4:122544447-122567266 (+)
DBA/2J ENSMUSG00185051773
 protein coding gene Chr4:124076795-124099614 (+)
FVB/NJ ENSMUSG00205039088
 protein coding gene Chr4:122303383-122326204 (+)
JF1/MsJ ENSUMUG00000028958
 protein coding gene Chr4:124721720-124745123 (+)
LP/J ENSMUSG00230033022
 protein coding gene Chr4:127870751-127902380 (+)
NOD/ShiLtJ ENSMUSG00190043391
 protein coding gene Chr4:122308262-122331076 (+)
NZO/HlLtJ ENSMUSG00225024569
 protein coding gene Chr4:133787697-133819329 (+)
PWK/PhJ ENSLUMG00010045480
 protein coding gene Chr4:121761853-121783033 (+)
SPRET/EiJ ENSMSPG00010043755
 protein coding gene Chr4:123829021-123836095 (+)
WSB/EiJ ENSIUOG00005041442
 protein coding gene Chr4:122169240-122192061 (+)



Homology
more
  • Human Ortholog
    TMEM234, transmembrane protein 234
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM234, transmembrane protein 234
  • Synonyms
    AASL548, C1orf91, dJ622L5.7, PRO1105, RP4-622L5
  • Links
    NCBI Gene ID: 56063
    UniProt: Q8WY98

  • Chr Location
    1p35.2; chr1:32214472-32222359 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    32
  • Chemically induced (other)
    2
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Tmem234
  • Find Mice (IMSR)
    37 strains or lines available
Homozygous mutant mice exhibited an increased median serum IgG2a response to ovalbumin challenge.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76799 NCBI Gene Model | MGI Sequence Detail 7878 C57BL/6J ±  kb
transcript NM_001368260 RefSeq | MGI Sequence Detail 1766 C57BL/6  
polypeptide Q8R1E7 UniProt | EBI | MGI Sequence Detail 140 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916240, MGI:1921320
References
more
  • Summaries
    All 36
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory