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Arpc2 Gene Detail
Summary
  • Symbol
    Arpc2
  • Name
    actin related protein 2/3 complex, subunit 2
  • Synonyms
    2210023N03Rik, p34-Arc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923959
    NCBI Gene: 76709
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:74275656-74307368 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 38.49 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    954 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923959
 protein coding gene Chr1:74275243-74307368 (+)
129S1/SvImJ ENSMUSG00200030818
 protein coding gene Chr1:71938183-71970301 (+)
A/J ENSMUSG00195008123
 protein coding gene Chr1:71363099-71395197 (+)
AKR/J ENSMUSG00220010215
 protein coding gene Chr1:71508876-71540982 (+)
BALB/cJ ENSMUSG00180016612
 protein coding gene Chr1:71621923-71654053 (+)
C3H/HeJ ENSMUSG00175014766
 protein coding gene Chr1:71763494-71795590 (+)
C57BL/6NJ ENSMUSG00215013171
 protein coding gene Chr1:71667223-71699348 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014255
 protein coding gene Chr1:67786419-67819326 (+)
CAST/EiJ ENSTCUG00005026446
 protein coding gene Chr1:71390224-71421931 (+)
CBA/J ENSMUSG00210032103
 protein coding gene Chr1:71447751-71479842 (+)
DBA/2J ENSMUSG00185028885
 protein coding gene Chr1:72541541-72573644 (+)
FVB/NJ ENSMUSG00205029463
 protein coding gene Chr1:71116829-71148961 (+)
JF1/MsJ ENSUMUG00000004185
 protein coding gene Chr1:71438237-71470366 (+)
LP/J ENSMUSG00230010142
 protein coding gene Chr1:72531370-72563484 (+)
NOD/ShiLtJ ENSMUSG00190031552
 protein coding gene Chr1:71673834-71705990 (+)
NZO/HlLtJ ENSMUSG00225039270
 protein coding gene Chr1:75746487-75778601 (+)
PWK/PhJ ENSLUMG00010012832
 protein coding gene Chr1:71016116-71048633 (+)
SPRET/EiJ ENSMSPG00010017329
 protein coding gene Chr1:73117470-73150320 (+)
WSB/EiJ ENSIUOG00005011889
 protein coding gene Chr1:71295586-71327691 (+)



Homology
more
  • Human Ortholog
    ARPC2, actin related protein 2/3 complex subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARPC2, actin related protein 2/3 complex subunit 2
  • Synonyms
    ARC34, p34-Arc, PNAS-139, PRO2446
  • Links
    NCBI Gene ID: 10109
    UniProt: O15144

  • Chr Location
    2q35; chr2:218216630-218254356 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    89
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    2
  • cDNA Data
    233
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76709 NCBI Gene Model | MGI Sequence Detail 31713 C57BL/6J ±  kb
    transcript NM_029711 RefSeq | MGI Sequence Detail 1599 C57BL/6  
    polypeptide Q9CVB6 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 234
      cDNA 234
      Antibodies 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 70
      Developmental Gene Expression 3
      Gene Ontology 14
      Phenotypes 27
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:378796 Lu Y, et al., Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration. Elife. 2026 Jan 29;14
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory