About   Help   FAQ
Got1l1 Gene Detail
Summary
  • Symbol
    Got1l1
  • Name
    glutamic-oxaloacetic transaminase 1-like 1
  • Synonyms
    1700083M11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923865
    NCBI Gene: 76615
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:27687487-27713856 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 15.92 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    909 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923865
 protein coding gene Chr8:27687487-27713872 (-)
129S1/SvImJ ENSMUSG00200020888
 protein coding gene Chr8:22777304-22803677 (-)
A/J ENSMUSG00195005171
 protein coding gene Chr8:23285889-23312256 (-)
AKR/J ENSMUSG00220024701
 protein coding gene Chr8:22926439-22952884 (-)
BALB/cJ ENSMUSG00180005242
 protein coding gene Chr8:22810484-22836849 (-)
C3H/HeJ ENSMUSG00175006664
 protein coding gene Chr8:22888944-22915385 (-)
C57BL/6NJ ENSMUSG00215011064
 protein coding gene Chr8:22774737-22801110 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030946
 protein coding gene Chr8:21666861-21672269 (-)
CAST/EiJ ENSTCUG00005020604
 protein coding gene Chr8:23076404-23102802 (-)
CBA/J ENSMUSG00210013994
 protein coding gene Chr8:22809527-22835890 (-)
DBA/2J ENSMUSG00185035203
 protein coding gene Chr8:28628529-28654969 (-)
FVB/NJ ENSMUSG00205003030
 protein coding gene Chr8:22315156-22341522 (-)
JF1/MsJ ENSUMUG00000006220
 protein coding gene Chr8:30482997-30509334 (-)
LP/J ENSMUSG00230014176
 protein coding gene Chr8:32369676-32396045 (-)
NOD/ShiLtJ ENSMUSG00190003990
 protein coding gene Chr8:22852907-22879272 (-)
NZO/HlLtJ ENSMUSG00225018677
 protein coding gene Chr8:36002037-36028512 (-)
PWK/PhJ ENSLUMG00010025511
 protein coding gene Chr8:22862125-22888483 (-)
SPRET/EiJ ENSMSPG00010016197
 protein coding gene Chr8:23150080-23181382 (-)
WSB/EiJ ENSIUOG00005009015
 protein coding gene Chr8:23534491-23560988 (-)



Homology
more
  • Human Ortholog
    GOT1L1, glutamic-oxaloacetic transaminase 1 like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GOT1L1, glutamic-oxaloacetic transaminase 1 like 1
  • Links
    NCBI Gene ID: 137362
    UniProt: Q8NHS2

  • Chr Location
    8p11.23; chr8:37934281-37940124 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhbit slight decreased glutamate and glutamine levels in the hippocampus.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039720 Ensembl Gene Model | MGI Sequence Detail 26370 C57BL/6J ±  kb
transcript ENSMUST00000038174 Ensembl | MGI Sequence Detail 1356 Not Applicable  
polypeptide ENSMUSP00000041337 Ensembl | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031376 putative aspartate aminotransferase, cytoplasmic 2
    (term hierarchy)
  • PDB
    9IJJ
  • EC
    2.6.1.1
  • InterPro Domains
    IPR004839 Aminotransferase, class I/classII, large domain
    IPR000796 Aspartate/other aminotransferase
    IPR015424 Pyridoxal phosphate-dependent transferase
    IPR015421 Pyridoxal phosphate-dependent transferase, major domain
    IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory