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Fam187b Gene Detail
Summary
  • Symbol
    Fam187b
  • Name
    family with sequence similarity 187, member B
  • Synonyms
    1700020B09Rik, Tmem162
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923665
    NCBI Gene: 76415
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30673219-30689151 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 19.28 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    581 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923665
protein coding gene Chr7:30673215-30689151 (+)
129S1/SvImJ ENSMUSG00200022838
protein coding gene Chr7:20442251-20459536 (+)
A/J ENSMUSG00195039718
protein coding gene Chr7:23118264-23135569 (+)
AKR/J ENSMUSG00220046550
protein coding gene Chr7:21342390-21359768 (-)
BALB/cJ ENSMUSG00180014758
protein coding gene Chr7:21177753-21195058 (+)
C3H/HeJ ENSMUSG00175034537
protein coding gene Chr7:22262330-22279631 (+)
C57BL/6NJ ENSMUSG00215008263
protein coding gene Chr7:20364530-20381835 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029555
protein coding gene Chr7:30174360-30191132 (+)
CAST/EiJ ENSTCUG00005040384
protein coding gene Chr7:22150084-22166165 (+)
CBA/J ENSMUSG00210025041
protein coding gene Chr7:21424937-21442240 (+)
DBA/2J ENSMUSG00185050807
protein coding gene Chr7:24500195-24516274 (+)
FVB/NJ ENSMUSG00205010012
protein coding gene Chr7:21174414-21191719 (+)
JF1/MsJ ENSUMUG00000029537
protein coding gene Chr7:28941627-28957723 (+)
LP/J ENSMUSG00230053525
protein coding gene Chr7:29675377-29692669 (+)
NOD/ShiLtJ ENSMUSG00190007655
protein coding gene Chr7:20842581-20859880 (+)
NZO/HlLtJ ENSMUSG00225024036
protein coding gene Chr7:28506793-28524236 (+)
PWK/PhJ ENSLUMG00010018003
protein coding gene Chr7:20869133-20885234 (+)
SPRET/EiJ ENSMSPG00010034348
protein coding gene Chr7:20241179-20256962 (+)
WSB/EiJ ENSIUOG00005049982
protein coding gene Chr7:15120037-15137354 (+)



Homology
more
  • Human Ortholog
    FAM187B, family with sequence similarity 187 member B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM187B, family with sequence similarity 187 member B
  • Synonyms
    TMEM162
  • Links
    NCBI Gene ID: 148109
    UniProt: Q17R55

  • Chr Location
    19q13.12; chr19:35224800-35228739 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a knock-out allele exhibit normal fertility; adult males show no significant changes in relative testis weight, sperm morphology, testis and epididymis histology, or sperm motility parameters.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76415 NCBI Gene Model | MGI Sequence Detail 15933 C57BL/6J ±  kb
transcript NM_001242647 RefSeq | MGI Sequence Detail 1471 C57BL/6  
polypeptide Q0VAY3 UniProt | EBI | MGI Sequence Detail 358 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:385300 Chang HY, et al., Mouse genome engineering uncovers 18 genes dispensable for male reproduction. Andrology. 2026 Mar;14(3):833-846

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory