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Inka2 Gene Detail
Summary
  • Symbol
    Inka2
  • Name
    inka box actin regulator 2
  • Synonyms
    6530418L21Rik, Fam212b, Inka2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923497
    NCBI Gene: 109050
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:105611915-105628158 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    468 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923497
 protein coding gene Chr3:105611915-105628158 (+)
129S1/SvImJ ENSMUSG00200034322
 protein coding gene Chr3:102211456-102227741 (+)
A/J ENSMUSG00195023687
 protein coding gene Chr3:102632008-102648223 (+)
AKR/J ENSMUSG00220027286
 protein coding gene Chr3:101003920-101020220 (+)
BALB/cJ ENSMUSG00180016977
 protein coding gene Chr3:102577354-102593613 (+)
C3H/HeJ ENSMUSG00175027730
 protein coding gene Chr3:102112232-102128488 (+)
C57BL/6NJ ENSMUSG00215029284
 protein coding gene Chr3:102884355-102900653 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025475
 protein coding gene Chr3:99732209-99748599 (+)
CAST/EiJ ENSTCUG00005019849
 protein coding gene Chr3:102842983-102859233 (+)
CBA/J ENSMUSG00210007214
 protein coding gene Chr3:102734228-102750477 (+)
DBA/2J ENSMUSG00185020517
 protein coding gene Chr3:103218411-103234706 (+)
FVB/NJ ENSMUSG00205016002
 protein coding gene Chr3:101788112-101804410 (+)
JF1/MsJ ENSUMUG00000021140
 protein coding gene Chr3:101958054-101974602 (+)
LP/J ENSMUSG00230014198
 protein coding gene Chr3:105139355-105155647 (+)
NOD/ShiLtJ ENSMUSG00190030221
 protein coding gene Chr3:103423393-103439643 (+)
NZO/HlLtJ ENSMUSG00225016742
 protein coding gene Chr3:107613191-107629701 (+)
PWK/PhJ ENSLUMG00010025937
 protein coding gene Chr3:102024336-102040943 (+)
SPRET/EiJ ENSMSPG00010029661
 protein coding gene Chr3:102216795-102229735 (+)
WSB/EiJ ENSIUOG00005004265
 protein coding gene Chr3:102749001-102765310 (+)



Homology
more
  • Human Ortholog
    INKA2, inka box actin regulator 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INKA2, inka box actin regulator 2
  • Synonyms
    C1orf183, FAM212B
  • Links
    NCBI Gene ID: 55924
    UniProt: Q9NTI7

  • Chr Location
    1p13.2; chr1:111680630-111755824 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Inka2
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Mice homozygous for a null allele exhibit impaired dendritic spine formation in pyramidal neuron.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    879
  • Tissues
    113
  • cDNA Data
    23
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109050 NCBI Gene Model | MGI Sequence Detail 16244 C57BL/6J ±  kb
transcript NM_175398 RefSeq | MGI Sequence Detail 4701 C57BL/6  
polypeptide Q80VY2 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 23
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:6155716
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory