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Ms4a18 Gene Detail
Summary
  • Symbol
    Ms4a18
  • Name
    membrane-spanning 4-domains, subfamily A, member 18
  • Synonyms
    5033428B15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923252
    NCBI Gene: 76002
  • Member of
    Ms4ac cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10974388-10995390 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 7.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    674 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923252
 protein coding gene Chr19:10974388-10995395 (-)
129S1/SvImJ ENSMUSG00200049049
 protein coding gene Chr19:7653475-7674477 (-)
A/J ENSMUSG00195052685
 protein coding gene Chr19:7866408-7887384 (-)
AKR/J ENSMUSG00220040577
 protein coding gene Chr19:7774351-7795357 (-)
BALB/cJ ENSMUSG00180036440
 protein coding gene Chr19:8228211-8249213 (-)
C3H/HeJ ENSMUSG00175010635
 protein coding gene Chr19:7499163-7520166 (-)
C57BL/6NJ ENSMUSG00215037455
 protein coding gene Chr19:7570788-7591790 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022710
 protein coding gene Chr19:8232029-8253907 (-)
CAST/EiJ ENSTCUG00005027101
 protein coding gene Chr19:7367976-7389082 (-)
CBA/J ENSMUSG00210041347
 protein coding gene Chr19:7697749-7718752 (-)
DBA/2J ENSMUSG00185051013
 protein coding gene Chr19:8107470-8128473 (-)
FVB/NJ ENSMUSG00205041796
 protein coding gene Chr19:7588853-7609837 (-)
JF1/MsJ ENSUMUG00000055005
 protein coding gene Chr19:8216053-8236920 (-)
LP/J ENSMUSG00230052197
 protein coding gene Chr19:9028100-9049102 (-)
NOD/ShiLtJ ENSMUSG00190035250
 protein coding gene Chr19:7326029-7347035 (-)
NZO/HlLtJ ENSMUSG00225045606
 protein coding gene Chr19:12736944-12757946 (-)
PWK/PhJ ENSLUMG00010007444
 protein coding gene Chr19:7613950-7634826 (-)
SPRET/EiJ ENSMSPG00010037340
 protein coding gene Chr19:7460236-7481219 (-)
WSB/EiJ ENSIUOG00005049684
 protein coding gene Chr19:7216067-7236853 (-)



Homology
more
  • Human Ortholog
    MS4A18, membrane spanning 4-domains A18
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MS4A18, membrane spanning 4-domains A18
  • Links
    NCBI Gene ID: 728588
    UniProt: Q3C1V0

  • Chr Location
    11q12.2; chr11:60724720-60745028 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76002 NCBI Gene Model | MGI Sequence Detail 21003 C57BL/6J ±  kb
transcript NM_001251849 RefSeq | MGI Sequence Detail 1459 C57BL/6  
polypeptide NP_001238778 RefSeq | MGI Sequence Detail 344 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007237 CD20-like, transmembrane domain
    IPR030417 Membrane-spanning 4-domains subfamily A
  • GlyGen
    J3QN01 1 site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 22
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:360865 Jiang HC, et al., CD20/MS4A1 is a mammalian olfactory receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators. Nat Commun. 2024 Apr 18;15(1):3360
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory