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Dcp1a Gene Detail
Summary
  • Symbol
    Dcp1a
  • Name
    decapping mRNA 1A
  • Synonyms
    1110066A22Rik, 4930568L04Rik, D14Ertd817e, Mitc1, SMIF
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923151
    NCBI Gene: 75901
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30201613-30249013 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 18.75 cM, cytoband B
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1355 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923151
 protein coding gene Chr14:30201492-30249020 (+)
129S1/SvImJ ENSMUSG00200037594
 protein coding gene Chr14:22023134-22071333 (+)
A/J ENSMUSG00195012579
 protein coding gene Chr14:23093407-23141700 (+)
AKR/J ENSMUSG00220031566
 protein coding gene Chr14:22207948-22256231 (+)
BALB/cJ ENSMUSG00180022543
 protein coding gene Chr14:22182017-22230303 (+)
C3H/HeJ ENSMUSG00175035602
 protein coding gene Chr14:22249300-22297583 (+)
C57BL/6NJ ENSMUSG00215030211
 protein coding gene Chr14:22492870-22541063 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019050
 protein coding gene Chr14:22793075-22839163 (+)
CAST/EiJ ENSTCUG00005022560
 protein coding gene Chr14:22329465-22377922 (+)
CBA/J ENSMUSG00210036256
 protein coding gene Chr14:22492262-22540542 (+)
DBA/2J ENSMUSG00185038597
 protein coding gene Chr14:26766889-26815087 (+)
FVB/NJ ENSMUSG00205031031
 protein coding gene Chr14:22351297-22399588 (+)
JF1/MsJ ENSUMUG00000030250
 protein coding gene Chr14:34024056-34072724 (+)
LP/J ENSMUSG00230035551
 protein coding gene Chr14:34047162-34095355 (+)
NOD/ShiLtJ ENSMUSG00190017316
 protein coding gene Chr14:22505878-22554164 (+)
NZO/HlLtJ ENSMUSG00225037175
 protein coding gene Chr14:28380544-28428827 (+)
PWK/PhJ ENSLUMG00010019558
 protein coding gene Chr14:10616677-10665346 (+)
SPRET/EiJ ENSMSPG00010037525
 protein coding gene Chr14:24167609-24215501 (+)
WSB/EiJ ENSIUOG00005012268
 protein coding gene Chr14:22317536-22365725 (+)



Homology
more
  • Human Ortholog
    DCP1A, decapping mRNA 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCP1A, decapping mRNA 1A
  • Synonyms
    HSA275986, Nbla00360, SMAD4IP1, SMIF
  • Links
    NCBI Gene ID: 55802
    UniProt: Q9NPI6

  • Chr Location
    3p21.1; chr3:53283429-53347683 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit embryonic growth retardation and die around E10.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    675
  • Tissues
    43
  • cDNA Data
    120
  • Literature Summary
    21
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75901 NCBI Gene Model | MGI Sequence Detail 47401 C57BL/6J ±  kb
transcript NM_133761 RefSeq | MGI Sequence Detail 5525 ZRU/MplStud  
polypeptide Q91YD3 UniProt | EBI | MGI Sequence Detail 602 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 122
    cDNA 120
    Primer pair 2
    Antibodies 5

    Microarray probesets 5
Other
Accession IDs
less
MGI:1289310, MGI:1916184, MGI:2145732
References
more
  • Summaries
    All 77
    Developmental Gene Expression 21
    Gene Ontology 15
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:361907 Wu J, et al., Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip. Adv Sci (Weinh). 2025 Feb;12(8):e2411732
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory