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Pramex1 Gene Detail
Summary
  • Symbol
    Pramex1
  • Name
    PRAME like, X-linked 1
  • Synonyms
    4930534P07Rik, Prame
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923079
    NCBI Gene: 75829
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:134513751-134528454 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 57.26 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923079
 protein coding gene ChrX:134513662-134528454 (-)
129S1/SvImJ ENSMUSG00200044163
 protein coding gene ChrX:113585869-113600576 (-)
A/J ENSMUSG00195046987
 protein coding gene ChrX:117372500-117387207 (-)
AKR/J ENSMUSG00220012912
 protein coding gene ChrX:110819331-110834040 (-)
BALB/cJ ENSMUSG00180036790
 protein coding gene ChrX:113804283-113818988 (-)
C3H/HeJ ENSMUSG00175031164
 protein coding gene ChrX:117739426-117754133 (-)
C57BL/6NJ ENSMUSG00215044747
 protein coding gene ChrX:114215707-114230410 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033405
 protein coding gene ChrX:124394320-124408960 (-)
CAST/EiJ ENSTCUG00005039823
 protein coding gene ChrX:114897167-114911567 (+)
CBA/J ENSMUSG00210038761
 protein coding gene ChrX:114675129-114689834 (-)
DBA/2J ENSMUSG00185029957
 protein coding gene ChrX:128566626-128581333 (-)
FVB/NJ ENSMUSG00205024557
 protein coding gene ChrX:113027226-113041928 (-)
JF1/MsJ ENSUMUG00000028114
 protein coding gene ChrX:147698537-147713235 (-)
LP/J ENSMUSG00230037021
 protein coding gene ChrX:135194565-135209272 (-)
NOD/ShiLtJ ENSMUSG00190028114
 protein coding gene ChrX:114066361-114081064 (-)
NZO/HlLtJ ENSMUSG00225036339
 protein coding gene ChrX:139795588-139810294 (-)
PWK/PhJ ENSLUMG00010040755
 protein coding gene ChrX:112464437-112479128 (-)
SPRET/EiJ ENSMSPG00010036930
 protein coding gene ChrX:117033029-117039638 (-)
WSB/EiJ no annotation



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031411 Ensembl Gene Model | MGI Sequence Detail 14704 C57BL/6J ±  kb
    transcript ENSMUST00000113159 Ensembl | MGI Sequence Detail 2267 Not Applicable  
    polypeptide ENSMUSP00000108784 Ensembl | MGI Sequence Detail 462 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR032675 Leucine-rich repeat domain superfamily
      IPR050694 LRRC14/PRAME
      IPR060377 PRAME-like, C-terminal LRR domain
      IPR060378 PRAME-like, N-terminal domain
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6437226
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Diseases 1
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:360547 Yang M, et al., Synergistic enhancement of the mouse Pramex1 and Pramel1 in repressing retinoic acid (RA) signaling during gametogenesis. Cell Biosci. 2024 Feb 23;14(1):28
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory