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Prl7b1 Gene Detail
Summary
  • Symbol
    Prl7b1
  • Name
    prolactin family 7, subfamily b, member 1
  • Synonyms
    1600014J19Rik, PLP-N, Prlpn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922846
    NCBI Gene: 75596
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27785802-27794565 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.55 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922846
 protein coding gene Chr13:27785795-27794565 (-)
129S1/SvImJ ENSMUSG00200028053
 protein coding gene Chr13:24945554-24954317 (-)
A/J ENSMUSG00195037780
 protein coding gene Chr13:24090853-24099616 (-)
AKR/J ENSMUSG00220012930
 protein coding gene Chr13:23896950-23905713 (-)
BALB/cJ ENSMUSG00180020409
 protein coding gene Chr13:24396071-24404834 (-)
C3H/HeJ ENSMUSG00175031748
 protein coding gene Chr13:24418826-24427589 (-)
C57BL/6NJ ENSMUSG00215007199
 protein coding gene Chr13:24550692-24559455 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018373
 protein coding gene Chr13:23267355-23276271 (-)
CAST/EiJ ENSTCUG00005009340
 protein coding gene Chr13:24578977-24587738 (-)
CBA/J ENSMUSG00210026746
 protein coding gene Chr13:24362994-24371757 (-)
DBA/2J ENSMUSG00185019371
 protein coding gene Chr13:25177872-25186635 (-)
FVB/NJ ENSMUSG00205018556
 protein coding gene Chr13:24175030-24183793 (-)
JF1/MsJ ENSUMUG00000009914
 protein coding gene Chr13:24824961-24833723 (-)
LP/J ENSMUSG00230016511
 protein coding gene Chr13:34506324-34515087 (-)
NOD/ShiLtJ ENSMUSG00190034819
 protein coding gene Chr13:24159909-24168672 (-)
NZO/HlLtJ ENSMUSG00225045240
 protein coding gene Chr13:28285466-28294229 (-)
PWK/PhJ ENSLUMG00010028434
 protein coding gene Chr13:23643358-23652121 (-)
SPRET/EiJ ENSMSPG00010023289
 protein coding gene Chr13:23597966-23607063 (-)
WSB/EiJ ENSIUOG00005015709
 protein coding gene Chr13:23741111-23749875 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit enhanced fetal growth and survival following exposure of dams to low oxygen conditions.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    633
  • Tissues
    17
  • cDNA Data
    11
  • Literature Summary
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021347 Ensembl Gene Model | MGI Sequence Detail 8764 C57BL/6J ±  kb
    transcript ENSMUST00000080595 Ensembl | MGI Sequence Detail 925 Not Applicable  
    polypeptide ENSMUSP00000079431 Ensembl | MGI Sequence Detail 251 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 12
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 14
      Gene Ontology 3
      Phenotypes 17
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:369753 Cai JX, et al., Chemerin sustains the growth of spongiotrophoblast and sinusoidal trophoblast giant cells through fatty acid oxidation. BMC Biol. 2025 Jul 3;23(1):199
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory