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Spata45 Gene Detail
Summary
  • Symbol
    Spata45
  • Name
    spermatogenesis associated 45
  • Synonyms
    1700022P22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922808
    NCBI Gene: 75558
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:190768836-190775139 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 96.28 cM, cytoband H6
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922808
protein coding gene Chr1:190768106-190775139 (+)
129S1/SvImJ ENSMUSG00200003436
protein coding gene Chr1:188548573-188554775 (+)
A/J ENSMUSG00195007988
protein coding gene Chr1:188128524-188134596 (+)
AKR/J ENSMUSG00220004478
protein coding gene Chr1:187372378-187378449 (+)
BALB/cJ ENSMUSG00180016231
protein coding gene Chr1:188193957-188200046 (+)
C3H/HeJ ENSMUSG00175021967
protein coding gene Chr1:188381969-188388045 (+)
C57BL/6NJ ENSMUSG00215011952
protein coding gene Chr1:187601317-187607624 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015043
protein coding gene Chr1:180840938-180846776 (+)
CAST/EiJ ENSTCUG00005001866
protein coding gene Chr1:186156982-186163161 (+)
CBA/J ENSMUSG00210003320
protein coding gene Chr1:188043651-188049849 (+)
DBA/2J ENSMUSG00185010440
protein coding gene Chr1:192656903-192663101 (+)
FVB/NJ ENSMUSG00205003938
protein coding gene Chr1:187040002-187046078 (+)
JF1/MsJ ENSUMUG00000005561
protein coding gene Chr1:191642145-191648366 (+)
LP/J ENSMUSG00230021137
protein coding gene Chr1:192192860-192198940 (+)
NOD/ShiLtJ ENSMUSG00190027060
protein coding gene Chr1:188027176-188033378 (+)
NZO/HlLtJ ENSMUSG00225015333
protein coding gene Chr1:195953833-195960027 (+)
PWK/PhJ ENSLUMG00010006223
protein coding gene Chr1:186875874-186882076 (+)
SPRET/EiJ ENSMSPG00010022502
protein coding gene Chr1:190415063-190420865 (+)
WSB/EiJ ENSIUOG00005004352
protein coding gene Chr1:187377838-187384084 (+)



Homology
more
  • Human Ortholog
    SPATA45, spermatogenesis associated 45
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA45, spermatogenesis associated 45
  • Synonyms
    C1orf227
  • Links
    NCBI Gene ID: 149643
    UniProt: Q537H7

  • Chr Location
    1q32.3; chr1:212830141-212847649 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000057072 Ensembl Gene Model | MGI Sequence Detail 6304 C57BL/6J ±  kb
    transcript ENSMUST00000192151 Ensembl | MGI Sequence Detail 443 Not Applicable  
    polypeptide ENSMUSP00000141721 Ensembl | MGI Sequence Detail 97 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 5
    References
    more
    • Summaries
      All 22
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:348435 Suzuki A, et al., Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024;:104252

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/01/2026
    MGI 6.24
    The Jackson Laboratory