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Nscme3l Gene Detail
Summary
  • Symbol
    Nscme3l
  • Name
    NSE3 homolog, SMC5-SMC6 complex component like
  • Synonyms
    1700020D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922805
    NCBI Gene: 75555
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5552795-5553815 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.34 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922805
 protein coding gene Chr19:5552795-5553815 (-)
129S1/SvImJ ENSMUSG00200047366
 protein coding gene Chr19:2314723-2315743 (-)
A/J ENSMUSG00195043293
 protein coding gene Chr19:2709065-2710085 (-)
AKR/J ENSMUSG00220042143
 protein coding gene Chr19:2482187-2483207 (-)
BALB/cJ ENSMUSG00180049974
 protein coding gene Chr19:3083787-3084807 (-)
C3H/HeJ ENSMUSG00175010050
 protein coding gene Chr19:2334000-2335020 (-)
C57BL/6NJ ENSMUSG00215039510
 protein coding gene Chr19:2552927-2553947 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022557
 protein coding gene Chr19:2240105-2241104 (-)
CAST/EiJ ENSTCUG00005042956
 protein coding gene Chr19:2473756-2474776 (-)
CBA/J ENSMUSG00210048956
 protein coding gene Chr19:2336301-2337321 (-)
DBA/2J ENSMUSG00185046204
 protein coding gene Chr19:2712766-2713786 (-)
FVB/NJ ENSMUSG00205046582
 protein coding gene Chr19:2719670-2720690 (-)
JF1/MsJ ENSUMUG00000016625
 protein coding gene Chr19:2690489-2691509 (-)
LP/J ENSMUSG00230052648
 protein coding gene Chr19:3621632-3622652 (-)
NOD/ShiLtJ ENSMUSG00190050534
 protein coding gene Chr19:2243576-2244596 (-)
NZO/HlLtJ ENSMUSG00225026612
 protein coding gene Chr19:7330399-7331419 (-)
PWK/PhJ ENSLUMG00010003515
 protein coding gene Chr19:2459166-2460186 (-)
SPRET/EiJ ENSMSPG00010047594
 protein coding gene Chr19:2449159-2450179 (-)
WSB/EiJ ENSIUOG00005050694
 protein coding gene Chr19:2351699-2352719 (-)



Homology
more
  • Human Ortholog
    NSMCE3, NSE3 component of SMC5/6 complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NSMCE3, NSE3 component of SMC5/6 complex
  • Synonyms
    HCA4, LICS, MAGEG1, MAGEL3, NDNL2, NSE3
  • Links
    NCBI Gene ID: 56160
    UniProt: Q96MG7

  • Chr Location
    15q13.1; chr15:29264989-29269822 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    22
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75555 NCBI Gene Model | MGI Sequence Detail 1021 C57BL/6J ±  kb
transcript NM_023781 RefSeq | MGI Sequence Detail 1087 C57BL/6  
polypeptide NP_076270 RefSeq | MGI Sequence Detail 294 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 3
Other
Accession IDs
less
MGI:6449757
References
more
  • Summaries
    All 23
    Gene Ontology 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:307015 Jeong J, et al., Characterization of MAGEG2 with testis-specific expression in mice. Asian J Androl. 2017 Nov-Dec;19(6):659-665
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory