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Izumo2 Gene Detail
Summary
  • Symbol
    Izumo2
  • Name
    IZUMO family member 2
  • Synonyms
    1700023D19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922760
    NCBI Gene: 75510
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44358166-44369268 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.89 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    486 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922760
protein coding gene Chr7:44358122-44369272 (+)
129S1/SvImJ ENSMUSG00200025822
protein coding gene Chr7:31951628-31963196 (+)
A/J ENSMUSG00195047635
protein coding gene Chr7:35979743-35991297 (+)
AKR/J ENSMUSG00220007674
protein coding gene Chr7:30284565-30296127 (+)
BALB/cJ ENSMUSG00180035743
protein coding gene Chr7:32855137-32866685 (+)
C3H/HeJ ENSMUSG00175036935
protein coding gene Chr7:33387559-33399126 (+)
C57BL/6NJ ENSMUSG00215043480
protein coding gene Chr7:32648601-32660173 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029672
protein coding gene Chr7:46649143-46661968 (+)
CAST/EiJ ENSTCUG00005046100
protein coding gene Chr7:36364673-36376208 (+)
CBA/J ENSMUSG00210047813
protein coding gene Chr7:33758935-33770495 (+)
DBA/2J ENSMUSG00185043098
protein coding gene Chr7:37631573-37643122 (+)
FVB/NJ ENSMUSG00205039583
protein coding gene Chr7:33304152-33315716 (+)
JF1/MsJ ENSUMUG00000016131
protein coding gene Chr7:42120372-42131827 (+)
LP/J ENSMUSG00230050894
protein coding gene Chr7:43054531-43065911 (+)
NOD/ShiLtJ ENSMUSG00190026677
protein coding gene Chr7:33631919-33643484 (+)
NZO/HlLtJ ENSMUSG00225016631
protein coding gene Chr7:41265368-41276716 (+)
PWK/PhJ ENSLUMG00010036118
protein coding gene Chr7:32589462-32601018 (+)
SPRET/EiJ ENSMSPG00010027892
protein coding gene Chr7:32367720-32379271 (+)
WSB/EiJ ENSIUOG00005020771
protein coding gene Chr7:34177359-34188944 (+)



Homology
more
  • Human Ortholog
    IZUMO2, IZUMO family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IZUMO2, IZUMO family member 2
  • Synonyms
    C19orf41, PLAL6978, PRO21961, SCRL
  • Links
    NCBI Gene ID: 126123
    UniProt: Q6UXV1

  • Chr Location
    19q13.33; chr19:50152537-50163281 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000066500 Ensembl Gene Model | MGI Sequence Detail 11103 C57BL/6J ±  kb
    transcript ENSMUST00000085422 Ensembl | MGI Sequence Detail 632 Not Applicable  
    polypeptide ENSMUSP00000082543 Ensembl | MGI Sequence Detail 193 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 29
      Gene Ontology 2
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    09/01/2026
    MGI 6.24
    The Jackson Laboratory