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Spata19 Gene Detail
Summary
  • Symbol
    Spata19
  • Name
    spermatogenesis associated 19
  • Synonyms
    1700001L23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922719
    NCBI Gene: 75469
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:27308103-27313007 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 12.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    222 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922719
protein coding gene Chr9:27308096-27313081 (+)
129S1/SvImJ ENSMUSG00200007340
protein coding gene Chr9:24298612-24303519 (+)
A/J ENSMUSG00195005497
protein coding gene Chr9:24104704-24109611 (+)
AKR/J ENSMUSG00220010299
protein coding gene Chr9:24102637-24107544 (+)
BALB/cJ ENSMUSG00180006196
protein coding gene Chr9:24238865-24243772 (+)
C3H/HeJ ENSMUSG00175019469
protein coding gene Chr9:24215290-24220197 (+)
C57BL/6NJ ENSMUSG00215006956
protein coding gene Chr9:24200670-24205570 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031929
protein coding gene Chr9:23228117-23233079 (+)
CAST/EiJ ENSTCUG00005018480
protein coding gene Chr9:24199716-24204636 (+)
CBA/J ENSMUSG00210022072
protein coding gene Chr9:24258939-24263846 (+)
DBA/2J ENSMUSG00185002099
protein coding gene Chr9:24297336-24302243 (+)
FVB/NJ ENSMUSG00205004381
protein coding gene Chr9:24587558-24592465 (+)
JF1/MsJ ENSUMUG00000009232
protein coding gene Chr9:24438831-24443753 (+)
LP/J ENSMUSG00230004215
protein coding gene Chr9:24704581-24709488 (+)
NOD/ShiLtJ ENSMUSG00190005673
protein coding gene Chr9:24290797-24295704 (+)
NZO/HlLtJ ENSMUSG00225014852
protein coding gene Chr9:24717661-24722568 (+)
PWK/PhJ ENSLUMG00010009057
protein coding gene Chr9:24323101-24327998 (+)
SPRET/EiJ ENSMSPG00010002078
protein coding gene Chr9:24642504-24647300 (+)
WSB/EiJ ENSIUOG00005015154
protein coding gene Chr9:23779992-23784907 (+)



Homology
more
  • Human Ortholog
    SPATA19, spermatogenesis associated 19
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA19, spermatogenesis associated 19
  • Synonyms
    CT132, SPAS1, spergen1
  • Links
    NCBI Gene ID: 219938
    UniProt: Q7Z5L4

  • Chr Location
    11q25; chr11:133835930-133845538 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with loss of expression in the testes show male infertility with impaired progressive sperm motility and abnormalities in the mitochondrial sheath.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75469 NCBI Gene Model | MGI Sequence Detail 4905 C57BL/6J ±  kb
    transcript NM_029299 RefSeq | MGI Sequence Detail 711 C57BL/6  
    polypeptide Q9DAQ9 UniProt | EBI | MGI Sequence Detail 154 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000015484 spermatogenesis-associated protein 19, mitochondrial
    • InterPro Domains
      IPR028219 Spermatogenesis-associated protein 19, mitochondrial
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 29

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143258
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:301706 Mi Y, et al., Spata19 is critical for sperm mitochondrial function and male fertility. Mol Reprod Dev. 2015 Nov;82(11):907-13

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory