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Fam243 Gene Detail
Summary
  • Symbol
    Fam243
  • Name
    family with sequence similarity 243
  • Synonyms
    4930563D23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922578
    NCBI Gene: 75328
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:92115653-92118329 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 53.56 cM, cytoband C4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    203 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922578
 protein coding gene Chr16:92115651-92118329 (-)
129S1/SvImJ ENSMUSG00200036969
 protein coding gene Chr16:89045261-89047937 (-)
A/J ENSMUSG00195027043
 protein coding gene Chr16:88802535-88805211 (-)
AKR/J ENSMUSG00220015174
 protein coding gene Chr16:89032250-89034926 (-)
BALB/cJ ENSMUSG00180014355
 protein coding gene Chr16:88876627-88879303 (-)
C3H/HeJ ENSMUSG00175014068
 protein coding gene Chr16:89213896-89216572 (-)
C57BL/6NJ ENSMUSG00215020702
 protein coding gene Chr16:89004908-89007584 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020974
 protein coding gene Chr16:86711271-86713952 (-)
CAST/EiJ ENSTCUG00005017776
 protein coding gene Chr16:88555560-88558233 (-)
CBA/J ENSMUSG00210033052
 protein coding gene Chr16:89120094-89122770 (-)
DBA/2J ENSMUSG00185032244
 protein coding gene Chr16:89064552-89067228 (-)
FVB/NJ ENSMUSG00205015091
 protein coding gene Chr16:88839712-88842388 (-)
JF1/MsJ ENSUMUG00000041865
 protein coding gene Chr16:89203464-89206127 (-)
LP/J ENSMUSG00230030595
 protein coding gene Chr16:91591989-91594665 (-)
NOD/ShiLtJ ENSMUSG00190023203
 protein coding gene Chr16:89029693-89032369 (-)
NZO/HlLtJ ENSMUSG00225030694
 protein coding gene Chr16:94714520-94717196 (-)
PWK/PhJ ENSLUMG00010012697
 protein coding gene Chr16:88831566-88834238 (-)
SPRET/EiJ ENSMSPG00010028051
 protein coding gene Chr16:89971695-89974359 (-)
WSB/EiJ ENSIUOG00005020072
 protein coding gene Chr16:88936228-88938902 (-)



Homology
more
  • Human Ortholog
    C21orf140, chromosome 21 open reading frame 140
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C21orf140, chromosome 21 open reading frame 140
  • Synonyms
    FAM243A
  • Links
    NCBI Gene ID: 101928147
    UniProt: B9A014

  • Chr Location
    chr21:34400112-34401072 (-)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    77 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    606
  • Tissues
    1
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051728 Ensembl Gene Model | MGI Sequence Detail 2677 C57BL/6J ±  kb
transcript ENSMUST00000062638 Ensembl | MGI Sequence Detail 2677 Not Applicable  
polypeptide ENSMUSP00000049694 Ensembl | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR037728 Uncharacterized protein C21orf140-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:6162264
References
more
  • Summaries
    All 97
    Developmental Gene Expression 1
    Diseases 4
    Phenotypes 77
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:385727 Harada K, et al., Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome. Immunology. 2026 Mar;177(3):596-612
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory