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Tex50 Gene Detail
Summary
  • Symbol
    Tex50
  • Name
    testis expressed 50
  • Synonyms
    4930469G21Rik
Location &
Maps
more
  • Sequence Map
    Chr1:160984413-160986883 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 69.75 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922183
 protein coding gene Chr1:160982128-160986884 (-)
129S1/SvImJ ENSMUSG00200005820
 protein coding gene Chr1:158477672-158482425 (-)
A/J ENSMUSG00195022171
 protein coding gene Chr1:157802970-157807717 (-)
AKR/J ENSMUSG00220013695
 protein coding gene Chr1:157592770-157597528 (-)
BALB/cJ ENSMUSG00180035660
 protein coding gene Chr1:158039302-158044053 (-)
C3H/HeJ ENSMUSG00175036800
 protein coding gene Chr1:158112891-158117643 (-)
C57BL/6NJ ENSMUSG00215034159
 protein coding gene Chr1:158001033-158005789 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0002428
 antisense lncRNA gene Chr1:151762326-151767032 (-)
CAST/EiJ ENSTCUG00005019826
 protein coding gene Chr1:156636482-156641233 (-)
CBA/J ENSMUSG00210021062
 protein coding gene Chr1:158010642-158015395 (-)
DBA/2J ENSMUSG00185040807
 protein coding gene Chr1:162257427-162262178 (-)
FVB/NJ ENSMUSG00205009746
 protein coding gene Chr1:157087816-157092573 (-)
JF1/MsJ ENSUMUG00000020645
 protein coding gene Chr1:161418170-161422921 (-)
LP/J ENSMUSG00230011743
 protein coding gene Chr1:161879006-161883758 (-)
NOD/ShiLtJ ENSMUSG00190033675
 protein coding gene Chr1:157839611-157844368 (-)
NZO/HlLtJ ENSMUSG00225004373
 protein coding gene Chr1:165488964-165493720 (-)
PWK/PhJ ENSLUMG00010036243
 protein coding gene Chr1:156798177-156802930 (-)
SPRET/EiJ ENSMSPG00010041603
 protein coding gene Chr1:160217197-160219706 (-)
WSB/EiJ ENSIUOG00005015241
 protein coding gene Chr1:157398308-157403066 (-)



Homology
more
  • Human Ortholog
    TEX50, testis expressed 50
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEX50, testis expressed 50
  • Links
    NCBI Gene ID: 730159
    UniProt: A0A1B0GTY4

  • Chr Location
    1q25.1; chr1:173635338-173637130 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility. Spermatozoa exhibit globozoospermia, irregular flagellar bending and coiling of sperm tails, and impaired motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100502590 NCBI Gene Model | MGI Sequence Detail 2471 C57BL/6J ±  kb
    transcript NM_001195189 RefSeq | MGI Sequence Detail 953 C57BL/6  
    polypeptide Q9D5B7 UniProt | EBI | MGI Sequence Detail 189 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR038833 Testis-expressed protein 50
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:5898325
    References
    more
    • Summaries
      All 19
      Gene Ontology 1
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:382376 Haga S, et al., Testis expressed 50 is essential for maintaining sperm acrosome integrity during epididymal transit. Proc Natl Acad Sci U S A. 2025 Sep 9;122(36):e2507930122
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory