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Pmis2 Gene Detail
Summary
  • Symbol
    Pmis2
  • Name
    PMIS2 transmembrane protein
  • Synonyms
    1700071L20Rik, 4930479M11Rik
Location &
Maps
more
  • Sequence Map
    Chr7:30370147-30371030 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922177
 protein coding gene Chr7:30370147-30371030 (-)
129S1/SvImJ ENSMUSG00200022071
 protein coding gene Chr7:20150489-20151371 (-)
A/J ENSMUSG00195045299
 protein coding gene Chr7:22819143-22820021 (-)
AKR/J ENSMUSG00220052877
 protein coding gene Chr7:21661224-21662103 (+)
BALB/cJ ENSMUSG00180016545
 protein coding gene Chr7:20878627-20879506 (-)
C3H/HeJ ENSMUSG00175036116
 protein coding gene Chr7:21959189-21960072 (-)
C57BL/6NJ ENSMUSG00215010979
 protein coding gene Chr7:20061318-20062201 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029538
 protein coding gene Chr7:29905585-29906448 (-)
CAST/EiJ ENSTCUG00005039697
 protein coding gene Chr7:21861415-21862295 (-)
CBA/J ENSMUSG00210024738
 protein coding gene Chr7:21121805-21122688 (-)
DBA/2J ENSMUSG00185046064
 protein coding gene Chr7:24210713-24211594 (-)
FVB/NJ ENSMUSG00205012394
 protein coding gene Chr7:20871148-20872032 (-)
JF1/MsJ ENSUMUG00000055959
 protein coding gene Chr7:28656370-28657251 (-)
LP/J ENSMUSG00230052150
 protein coding gene Chr7:29381154-29382035 (-)
NOD/ShiLtJ ENSMUSG00190007697
 protein coding gene Chr7:20543503-20544381 (-)
NZO/HlLtJ ENSMUSG00225024339
 protein coding gene Chr7:28221654-28222535 (-)
PWK/PhJ ENSLUMG00010019949
 protein coding gene Chr7:20587930-20588811 (-)
SPRET/EiJ ENSMSPG00010042514
 protein coding gene Chr7:19949388-19950272 (-)
WSB/EiJ ENSIUOG00005050302
 protein coding gene Chr7:14832129-14833012 (-)



Homology
more
  • Human Ortholog
    PMIS2, PMIS2 transmembrane protein
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PMIS2, PMIS2 transmembrane protein
  • Synonyms
    IFITMD9
  • Links
    NCBI Gene ID: 111216276
    UniProt: A0A1W2PS18

  • Chr Location
    19q13.12; chr19:35586161-35587296 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal sperm physiology and male infertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    4
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      32
    • RefSeq
      2
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74927 NCBI Gene Model | MGI Sequence Detail 884 C57BL/6J ±  kb
    transcript NR_027848 RefSeq | MGI Sequence Detail 720 C57BL/6  
    polypeptide Q8CES1 UniProt | EBI | MGI Sequence Detail 96 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR007593 CD225/Dispanin family
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1920744
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:366270 Inoue N, et al., Noncanonical phagocytosis-like SEAL establishes mammalian fertilization. Cell Rep. 2025 Apr 22;44(4):115463
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory