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Tmem114 Gene Detail
Summary
  • Symbol
    Tmem114
  • Name
    transmembrane protein 114
  • Synonyms
    4930511J11Rik, Cldn26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921970
    NCBI Gene: 74720
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8227140-8243000 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 3.84 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    620 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921970
 protein coding gene Chr16:8227139-8243000 (-)
129S1/SvImJ ENSMUSG00200010598
 protein coding gene Chr16:5207701-5223562 (-)
A/J ENSMUSG00195010283
 protein coding gene Chr16:4757544-4773404 (-)
AKR/J ENSMUSG00220017244
 protein coding gene Chr16:5049353-5065211 (-)
BALB/cJ ENSMUSG00180007520
 protein coding gene Chr16:5009183-5025044 (-)
C3H/HeJ ENSMUSG00175025414
 protein coding gene Chr16:5200306-5216167 (-)
C57BL/6NJ ENSMUSG00215014754
 protein coding gene Chr16:4873537-4889398 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020428
 protein coding gene Chr16:4972132-4985002 (-)
CAST/EiJ ENSTCUG00005028578
 protein coding gene Chr16:5110469-5126031 (-)
CBA/J ENSMUSG00210011273
 protein coding gene Chr16:5217553-5233418 (-)
DBA/2J ENSMUSG00185009884
 protein coding gene Chr16:5162792-5178656 (-)
FVB/NJ ENSMUSG00205012250
 protein coding gene Chr16:5078025-5093887 (-)
JF1/MsJ ENSUMUG00000019529
 protein coding gene Chr16:5242687-5258577 (-)
LP/J ENSMUSG00230009028
 protein coding gene Chr16:7705329-7721190 (-)
NOD/ShiLtJ ENSMUSG00190021064
 protein coding gene Chr16:5254096-5269959 (-)
NZO/HlLtJ ENSMUSG00225031894
 protein coding gene Chr16:10945991-10961852 (-)
PWK/PhJ ENSLUMG00010016417
 protein coding gene Chr16:5077361-5093246 (-)
SPRET/EiJ ENSMSPG00010015555
 protein coding gene Chr16:5057795-5074377 (-)
WSB/EiJ ENSIUOG00005015364
 protein coding gene Chr16:5191255-5207130 (-)



Homology
more
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Links
    NCBI Gene ID: 283953
    UniProt: B3SHH9

  • Chr Location
    16p13.2; chr16:8526552-8590511 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    613
  • Tissues
    14
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74720 NCBI Gene Model | MGI Sequence Detail 15861 C57BL/6J ±  kb
    transcript NM_029070 RefSeq | MGI Sequence Detail 1406 C57BL/6  
    polypeptide Q9D563 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 1
      cDNA 5
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory