About   Help   FAQ
Ifitm7 Gene Detail
Summary
  • Symbol
    Ifitm7
  • Name
    interferon induced transmembrane protein 7
  • Synonyms
    4933438K12Rik, Mil4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921732
    NCBI Gene: 74482
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:13799566-13804731 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 9.66 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921732
 protein coding gene Chr16:13799563-13804752 (-)
129S1/SvImJ ENSMUSG00200041871
 protein coding gene Chr16:10782576-10785914 (-)
A/J ENSMUSG00195032870
 protein coding gene Chr16:10347559-10350899 (-)
AKR/J ENSMUSG00220044012
 protein coding gene Chr16:10644447-10647785 (-)
BALB/cJ ENSMUSG00180037318
 protein coding gene Chr16:10589953-10593295 (-)
C3H/HeJ ENSMUSG00175043401
 protein coding gene Chr16:10755873-10759300 (-)
C57BL/6NJ ENSMUSG00215024903
 protein coding gene Chr16:10464733-10468072 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020474
 protein coding gene Chr16:10471989-10473773 (-)
CAST/EiJ ENSTCUG00005043288
 protein coding gene Chr16:10633924-10644849 (-)
CBA/J ENSMUSG00210037182
 protein coding gene Chr16:10772840-10776267 (-)
DBA/2J ENSMUSG00185031532
 protein coding gene Chr16:10718360-10721787 (-)
FVB/NJ ENSMUSG00205031588
 protein coding gene Chr16:10704566-10707906 (-)
JF1/MsJ ENSUMUG00000039830
 protein coding gene Chr16:10809193-10817997 (-)
LP/J ENSMUSG00230043152
 protein coding gene Chr16:13278092-13281430 (-)
NOD/ShiLtJ ENSMUSG00190039805
 protein coding gene Chr16:10839457-10842795 (-)
NZO/HlLtJ ENSMUSG00225032098
 protein coding gene Chr16:16523344-16526682 (-)
PWK/PhJ ENSLUMG00010044834
 protein coding gene Chr16:10676242-10679702 (-)
SPRET/EiJ ENSMSPG00010042829
 protein coding gene Chr16:10663411-10668869 (-)
WSB/EiJ ENSIUOG00005034358
 protein coding gene Chr16:10800622-10806566 (-)



Homology
more
  • Human Ortholog
    IFITM3, interferon induced transmembrane protein 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFITM3, interferon induced transmembrane protein 3
  • Synonyms
    1-8U, DSPA2b, IP15
  • Links
    NCBI Gene ID: 10410
    UniProt: Q01628

  • Chr Location
    11p15.5; chr11:319675-329475 (-)  GRCh38
Human Diseases
more
  • Diseases
    3 with human IFITM1,IFITM3 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    697
  • Tissues
    17
  • cDNA Data
    6
  • Literature Summary
    4
Sequences &
Gene Models
less
  • All Sequences
    35
  • RefSeq
    2
  • UniProt
    4
Representative SequencesLengthStrain/SpeciesFlank
genomic 74482 NCBI Gene Model | MGI Sequence Detail 5166 C57BL/6J ±  kb
transcript NM_001270718 RefSeq | MGI Sequence Detail 865 C57BL/6  
polypeptide NP_001257647 RefSeq | MGI Sequence Detail 113 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR007593 CD225/Dispanin family
    IPR051517 Interferon-induced transmembrane antiviral protein
Molecular
Reagents
less
  • All nucleic 9
    cDNA 6
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:362502 Lv Y, et al., IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex. Adv Sci (Weinh). 2025 Mar 7;:e2501593
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory