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Lrrc2 Gene Detail
Summary
  • Symbol
    Lrrc2
  • Name
    leucine rich repeat containing 2
  • Synonyms
    2400002D05Rik, 4933431K03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921499
    NCBI Gene: 74249
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110780613-110813134 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.79 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1178 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921499
 protein coding gene Chr9:110780613-110813134 (+)
129S1/SvImJ ENSMUSG00200041588
 protein coding gene Chr9:107873280-107900129 (+)
A/J ENSMUSG00195036317
 protein coding gene Chr9:107167052-107193908 (+)
AKR/J ENSMUSG00220021750
 protein coding gene Chr9:107502471-107529318 (+)
BALB/cJ ENSMUSG00180030886
 protein coding gene Chr9:107621712-107648559 (+)
C3H/HeJ ENSMUSG00175033210
 protein coding gene Chr9:107837519-107864367 (+)
C57BL/6NJ ENSMUSG00215021381
 protein coding gene Chr9:107718349-107750874 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032750
 protein coding gene Chr9:106234714-106262380 (+)
CAST/EiJ ENSTCUG00005024132
 protein coding gene Chr9:107529744-107557904 (+)
CBA/J ENSMUSG00210027598
 protein coding gene Chr9:107559385-107586097 (+)
DBA/2J ENSMUSG00185032257
 protein coding gene Chr9:107885449-107912297 (+)
FVB/NJ ENSMUSG00205042978
 protein coding gene Chr9:107833545-107860390 (+)
JF1/MsJ ENSUMUG00000028495
 protein coding gene Chr9:107660307-107687029 (+)
LP/J ENSMUSG00230045274
 protein coding gene Chr9:108005388-108032230 (+)
NOD/ShiLtJ ENSMUSG00190043205
 protein coding gene Chr9:107473131-107499977 (+)
NZO/HlLtJ ENSMUSG00225024325
 protein coding gene Chr9:108263873-108290704 (+)
PWK/PhJ ENSLUMG00010037102
 protein coding gene Chr9:107667628-107694224 (+)
SPRET/EiJ ENSMSPG00010045003
 protein coding gene Chr9:109457382-109482946 (+)
WSB/EiJ ENSIUOG00005040203
 protein coding gene Chr9:106927521-106954218 (+)



Homology
more
  • Human Ortholog
    LRRC2, leucine rich repeat containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC2, leucine rich repeat containing 2
  • Links
    NCBI Gene ID: 79442
    UniProt: Q9BYS8

  • Chr Location
    3p21.31; chr3:46515385-46607097 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    669
  • Tissues
    2
  • cDNA Data
    18
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74249 NCBI Gene Model | MGI Sequence Detail 32522 C57BL/6J ±  kb
transcript NM_028838 RefSeq | MGI Sequence Detail 3657 ZRU/MplStud  
polypeptide Q8VDB8 UniProt | EBI | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1922983
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory