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Acoxl Gene Detail
Summary
  • Symbol
    Acoxl
  • Name
    acyl-Coenzyme A oxidase-like
  • Synonyms
    1200014P05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921371
    NCBI Gene: 74121
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:127680796-127965793 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6506 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921371
protein coding gene Chr2:127680717-127968172 (+)
129S1/SvImJ ENSMUSG00200048377
protein coding gene Chr2:124742544-125012538 (+)
A/J ENSMUSG00195029323
protein coding gene Chr2:124770139-125039579 (+)
AKR/J ENSMUSG00220041667
protein coding gene Chr2:124536322-124806322 (+)
BALB/cJ ENSMUSG00180044482
protein coding gene Chr2:124559131-124834102 (+)
C3H/HeJ ENSMUSG00175040864
protein coding gene Chr2:125100930-125385208 (+)
C57BL/6NJ ENSMUSG00215014321
protein coding gene Chr2:124617939-124887972 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024268
protein coding gene Chr2:120658473-120952017 (+)
CAST/EiJ ENSTCUG00005036715
protein coding gene Chr2:123897441-124173706 (+)
CBA/J ENSMUSG00210034811
protein coding gene Chr2:124951357-125235624 (+)
DBA/2J ENSMUSG00185032046
protein coding gene Chr2:124605491-124889769 (+)
FVB/NJ ENSMUSG00205029487
protein coding gene Chr2:123790875-124060849 (+)
JF1/MsJ ENSUMUG00000007731
protein coding gene Chr2:124456456-124740982 (+)
LP/J ENSMUSG00230033211
protein coding gene Chr2:126377956-126647913 (+)
NOD/ShiLtJ ENSMUSG00190012595
protein coding gene Chr2:124735761-125005753 (+)
NZO/HlLtJ ENSMUSG00225027350
protein coding gene Chr2:134284131-134554087 (+)
PWK/PhJ ENSLUMG00010034667
protein coding gene Chr2:124348126-124634216 (+)
SPRET/EiJ ENSMSPG00010030442
protein coding gene Chr2:126785626-127056900 (+)
WSB/EiJ ENSIUOG00005041216
protein coding gene Chr2:124546997-124817138 (+)



Homology
more
  • Human Ortholog
    ACOXL, acyl-CoA oxidase like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACOXL, acyl-CoA oxidase like
  • Synonyms
    ACOX4
  • Links
    NCBI Gene ID: 55289
    UniProt: Q9NUZ1

  • Chr Location
    2q13; chr2:110732524-111118548 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027380 Ensembl Gene Model | MGI Sequence Detail 284998 C57BL/6J ±  kb
    transcript ENSMUST00000028859 Ensembl | MGI Sequence Detail 2842 Not Applicable  
    polypeptide ENSMUSP00000028859 Ensembl | MGI Sequence Detail 632 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000003645 acyl-coenzyme A oxidase-like protein
    • EC
    • InterPro Domains
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR006091 Acyl-CoA dehydrogenase/oxidase, middle domain
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR012258 Acyl-CoA oxidase
      IPR055060 Acyl-CoA oxidase, C-alpha1 domain
      IPR002655 Acyl-CoA oxidase, C-terminal
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2139241
    References
    more
    • Summaries
      All 35
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory