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Gga2 Gene Detail
Summary
  • Symbol
    Gga2
  • Name
    golgi associated, gamma adaptin ear containing, ARF binding protein 2
  • Synonyms
    1200007E24Rik, mKIAA1080
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921355
    NCBI Gene: 74105
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:121585945-121620421 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 65.21 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    924 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921355
 protein coding gene Chr7:121585945-121620445 (-)
129S1/SvImJ ENSMUSG00200022287
 protein coding gene Chr7:108107348-108141757 (-)
A/J ENSMUSG00195038751
 protein coding gene Chr7:112643704-112678173 (-)
AKR/J ENSMUSG00220020012
 protein coding gene Chr7:106068079-106102595 (-)
BALB/cJ ENSMUSG00180032004
 protein coding gene Chr7:109299010-109333520 (-)
C3H/HeJ ENSMUSG00175021152
 protein coding gene Chr7:110012337-110046842 (-)
C57BL/6NJ ENSMUSG00215033225
 protein coding gene Chr7:109262346-109296852 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030413
 protein coding gene Chr7:124106585-124141515 (-)
CAST/EiJ ENSTCUG00005045236
 protein coding gene Chr7:112577529-112612292 (-)
CBA/J ENSMUSG00210023961
 protein coding gene Chr7:109740056-109774567 (-)
DBA/2J ENSMUSG00185040476
 protein coding gene Chr7:114086059-114120562 (-)
FVB/NJ ENSMUSG00205040979
 protein coding gene Chr7:109746334-109780858 (-)
JF1/MsJ ENSUMUG00000049902
 protein coding gene Chr7:119168585-119203587 (-)
LP/J ENSMUSG00230032931
 protein coding gene Chr7:120195161-120229570 (-)
NOD/ShiLtJ ENSMUSG00190019446
 protein coding gene Chr7:109938998-109973509 (-)
NZO/HlLtJ ENSMUSG00225038527
 protein coding gene Chr7:118444243-118478900 (-)
PWK/PhJ ENSLUMG00010012634
 protein coding gene Chr7:108279570-108314066 (-)
SPRET/EiJ ENSMSPG00010007847
 protein coding gene Chr7:109503759-109539433 (-)
WSB/EiJ ENSIUOG00005011559
 protein coding gene Chr7:110628809-110663232 (-)



Homology
more
  • Human Ortholog
    GGA2, golgi associated, gamma adaptin ear containing, ARF binding protein 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GGA2, golgi associated, gamma adaptin ear containing, ARF binding protein 2
  • Synonyms
    VEAR
  • Links
    NCBI Gene ID: 23062
    UniProt: Q9UJY4

  • Chr Location
    16p12.2; chr16:23462213-23524359 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 3 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit complete embryonic lethality. Mice homozygous for a different gene trapped allele show decreased birth weight, hypoglycemia and partial neonatal lethality, with all remaining mice dying within the first three weeks of life.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    653
  • Tissues
    16
  • cDNA Data
    116
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74105 NCBI Gene Model | MGI Sequence Detail 34477 C57BL/6J ±  kb
    transcript NM_028758 RefSeq | MGI Sequence Detail 4891 C57BL/6  
    polypeptide Q6P5E6 UniProt | EBI | MGI Sequence Detail 603 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 119
      cDNA 116
      Primer pair 2
      Other 1
      Antibodies 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 3
      Gene Ontology 11
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:336776 Fang R, et al., ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING. Immunity. 2023 Mar 14;56(3):500-515.e6
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory