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Wdr75 Gene Detail
Summary
  • Symbol
    Wdr75
  • Name
    WD repeat domain 75
  • Synonyms
    1300003A18Rik, 2410118I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920924
    NCBI Gene: 73674
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:45834326-45862779 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 23.87 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    893 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920924
 protein coding gene Chr1:45834313-45862798 (+)
129S1/SvImJ ENSMUSG00200001506
 protein coding gene Chr1:43476498-43504944 (+)
A/J ENSMUSG00195001842
 protein coding gene Chr1:43211865-43240312 (+)
AKR/J ENSMUSG00220003398
 protein coding gene Chr1:43101169-43129623 (+)
BALB/cJ ENSMUSG00180003146
 protein coding gene Chr1:43181198-43209651 (+)
C3H/HeJ ENSMUSG00175000053
 protein coding gene Chr1:43243081-43271533 (+)
C57BL/6NJ ENSMUSG00215003004
 protein coding gene Chr1:43157632-43186085 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014107
 protein coding gene Chr1:40155400-40183690 (+)
CAST/EiJ ENSTCUG00005000830
 protein coding gene Chr1:43149420-43180692 (+)
CBA/J ENSMUSG00210029002
 protein coding gene Chr1:42939680-42968128 (+)
DBA/2J ENSMUSG00185028509
 protein coding gene Chr1:44066431-44094877 (+)
FVB/NJ ENSMUSG00205003175
 protein coding gene Chr1:43096623-43125077 (+)
JF1/MsJ ENSUMUG00000000971
 protein coding gene Chr1:43107607-43136094 (+)
LP/J ENSMUSG00230000944
 protein coding gene Chr1:44057513-44085958 (+)
NOD/ShiLtJ ENSMUSG00190002498
 protein coding gene Chr1:43123393-43151844 (+)
NZO/HlLtJ ENSMUSG00225000504
 protein coding gene Chr1:47292651-47321092 (+)
PWK/PhJ ENSLUMG00010002389
 protein coding gene Chr1:42672452-42700936 (+)
SPRET/EiJ ENSMSPG00010012559
 protein coding gene Chr1:44394537-44422628 (+)
WSB/EiJ ENSIUOG00005003455
 protein coding gene Chr1:43034990-43063430 (+)



Homology
more
  • Human Ortholog
    WDR75, WD repeat domain 75
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR75, WD repeat domain 75
  • Synonyms
    NET16, UTP17
  • Links
    NCBI Gene ID: 84128
    UniProt: Q8IWA0

  • Chr Location
    2q32.2; chr2:189441429-189479063 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    190
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025995 Ensembl Gene Model | MGI Sequence Detail 28454 C57BL/6J ±  kb
transcript ENSMUST00000027139 Ensembl | MGI Sequence Detail 2953 Not Applicable  
polypeptide ENSMUSP00000027139 Ensembl | MGI Sequence Detail 830 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000029869 WD repeat-containing protein 75
    (term hierarchy)
  • InterPro Domains
    IPR060769 EIF3B-like, beta-propeller domain superfamily
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR053826 WD repeat-containing protein 75
    IPR057644 WD repeat-containing protein 75, second beta-propeller
Molecular
Reagents
less
  • All nucleic 190
    cDNA 190

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921401, MGI:2138661
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:19723 Nishiguchi S, et al., A survey of genes expressed in undifferentiated mouse embryonal carcinoma F9 cells: characterization of low-abundance mRNAs. J Biochem. 1994 Jul;116(1):128-39
  • Latest
    J:189611 Vrljicak P, et al., Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. PLoS One. 2012;7(7):e40815
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory