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Defb30 Gene Detail
Summary
  • Symbol
    Defb30
  • Name
    defensin beta 30
  • Synonyms
    2410125J01Rik, 4930449O14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920920
    NCBI Gene: 73670
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:63271536-63275313 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920920
 protein coding gene Chr14:63271536-63287409 (-)
129S1/SvImJ ENSMUSG00200027762
 protein coding gene Chr14:51872483-51876279 (-)
A/J ENSMUSG00195028676
 protein coding gene Chr14:52053308-52057079 (-)
AKR/J ENSMUSG00220026775
 protein coding gene Chr14:51400718-51404488 (-)
BALB/cJ ENSMUSG00180032936
 protein coding gene Chr14:51675206-51678973 (-)
C3H/HeJ ENSMUSG00175034487
 protein coding gene Chr14:53408313-53412110 (-)
C57BL/6NJ ENSMUSG00215048522
 protein coding gene Chr14:51598802-51602561 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019398
 protein coding gene Chr14:54188165-54205554 (-)
CAST/EiJ ENSTCUG00005033712
 protein coding gene Chr14:53338676-53342487 (-)
CBA/J ENSMUSG00210033700
 protein coding gene Chr14:52041217-52044988 (-)
DBA/2J ENSMUSG00185031199
 protein coding gene Chr14:57206121-57209917 (-)
FVB/NJ ENSMUSG00205033221
 protein coding gene Chr14:51558732-51562499 (-)
JF1/MsJ ENSUMUG00000043850
 protein coding gene Chr14:68400430-68404249 (-)
LP/J ENSMUSG00230034216
 protein coding gene Chr14:69235694-69239490 (-)
NOD/ShiLtJ ENSMUSG00190031809
 protein coding gene Chr14:51835946-51839717 (-)
NZO/HlLtJ ENSMUSG00225044822
 protein coding gene Chr14:59578108-59581871 (-)
PWK/PhJ ENSLUMG00010046720
 protein coding gene Chr14:51285988-51289759 (-)
SPRET/EiJ ENSMSPG00010030514
 protein coding gene Chr14:54776500-54778425 (-)
WSB/EiJ ENSIUOG00005036303
 protein coding gene Chr14:51282196-51285957 (-)



Homology
more
  • Human Ortholog
    DEFB135, defensin beta 135
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFB135, defensin beta 135
  • Links
    NCBI Gene ID: 613209
    UniProt: Q30KP9

  • Chr Location
    8p23.1; chr8:11982256-11984590 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Defb30
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73670 NCBI Gene Model | MGI Sequence Detail 3778 C57BL/6J ±  kb
transcript NM_001436269 RefSeq | MGI Sequence Detail 665 C57BL/6  
polypeptide Q30KN4 UniProt | EBI | MGI Sequence Detail 75 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:1925380
References
more
  • Summaries
    All 33
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory