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Spmip8 Gene Detail
Summary
  • Symbol
    Spmip8
  • Name
    sperm microtubule inner protein 8
  • Synonyms
    1700055M20Rik, Tepp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920657
    NCBI Gene: 73407
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:96038148-96053239 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 47.12 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    454 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920657
 protein coding gene Chr8:96037194-96053239 (+)
129S1/SvImJ ENSMUSGG00200054721
 protein coding gene Chr8:90413610-90414953 (+)
129S1/SvImJ ENSMUSG00200013982
 protein coding gene Chr8:90406561-90406756 (+)
A/J ENSMUSGG00195055149
 protein coding gene Chr8:90754250-90755593 (+)
A/J ENSMUSG00195027048
 protein coding gene Chr8:90747192-90747387 (+)
AKR/J ENSMUSG00220011401
 protein coding gene Chr8:90784027-90784222 (+)
AKR/J ENSMUSGG00220054722
 protein coding gene Chr8:90791086-90792429 (+)
BALB/cJ ENSMUSGG00180055548
 protein coding gene Chr8:90650531-90651874 (+)
BALB/cJ ENSMUSG00180003667
 protein coding gene Chr8:90643482-90643677 (+)
C3H/HeJ ENSMUSG00175002574
 protein coding gene Chr8:90690395-90690590 (+)
C3H/HeJ ENSMUSGG00175054841
 protein coding gene Chr8:90697455-90698798 (+)
C57BL/6NJ ENSMUSGG00215055620
 protein coding gene Chr8:90319009-90320352 (+)
C57BL/6NJ ENSMUSG00215001165
 protein coding gene Chr8:90311978-90312173 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031419
 protein coding gene Chr8:86800758-86817277 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054873
 protein coding gene Chr8:90632868-90634211 (+)
CBA/J ENSMUSG00210015008
 protein coding gene Chr8:90625813-90626008 (+)
DBA/2J ENSMUSGG00185057661
 protein coding gene Chr8:96741714-96743057 (+)
DBA/2J ENSMUSG00185022062
 protein coding gene Chr8:96734663-96734858 (+)
FVB/NJ ENSMUSG00205012364
 protein coding gene Chr8:89730933-89731128 (+)
FVB/NJ ENSMUSGG00205054264
 protein coding gene Chr8:89737981-89739324 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230007763
 protein coding gene Chr8:100386960-100387155 (+)
LP/J ENSMUSGG00230055744
 protein coding gene Chr8:100393995-100395338 (+)
NOD/ShiLtJ ENSMUSGG00190054858
 protein coding gene Chr8:90760042-90761385 (+)
NOD/ShiLtJ ENSMUSG00190012652
 protein coding gene Chr8:90753011-90753206 (+)
NZO/HlLtJ ENSMUSG00225010717
 protein coding gene Chr8:103796523-103796718 (+)
NZO/HlLtJ ENSMUSGG00225055648
 protein coding gene Chr8:103803575-103804918 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010006191
 protein coding gene Chr8:92487457-92498322 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SPMIP8, sperm microtubule inner protein 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMIP8, sperm microtubule inner protein 8
  • Synonyms
    TEPP
  • Links
    NCBI Gene ID: 374739
    UniProt: Q6URK8

  • Chr Location
    16q21; chr16:57976435-57988116 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73407 NCBI Gene Model | MGI Sequence Detail 15092 C57BL/6J ±  kb
transcript NM_199455 RefSeq | MGI Sequence Detail 898 C57BL/6  
polypeptide Q6IMH0 UniProt | EBI | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:7470729
References
more
  • Summaries
    All 25
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory