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Tmem192 Gene Detail
Summary
  • Symbol
    Tmem192
  • Name
    transmembrane protein 192
  • Synonyms
    3110005G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920317
    NCBI Gene: 73067
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:65399837-65421685 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 32.44 cM, cytoband B3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    724 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920317
 protein coding gene Chr8:65399801-65421688 (+)
129S1/SvImJ ENSMUSG00200032334
 protein coding gene Chr8:60232307-60254147 (+)
A/J ENSMUSG00195011777
 protein coding gene Chr8:60587682-60609554 (+)
AKR/J ENSMUSG00220005280
 protein coding gene Chr8:60420024-60441869 (+)
BALB/cJ ENSMUSG00180013827
 protein coding gene Chr8:60211312-60233160 (+)
C3H/HeJ ENSMUSG00175019015
 protein coding gene Chr8:60436213-60458061 (+)
C57BL/6NJ ENSMUSG00215022121
 protein coding gene Chr8:60223929-60245777 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031087
 protein coding gene Chr8:57504562-57530869 (+)
CAST/EiJ ENSTCUG00005006469
 protein coding gene Chr8:60041986-60066062 (+)
CBA/J ENSMUSG00210028405
 protein coding gene Chr8:60317182-60339029 (+)
DBA/2J ENSMUSG00185022360
 protein coding gene Chr8:66370045-66391893 (+)
FVB/NJ ENSMUSG00205011153
 protein coding gene Chr8:59669878-59691720 (+)
JF1/MsJ ENSUMUG00000007973
 protein coding gene Chr8:68634491-68656414 (+)
LP/J ENSMUSG00230005942
 protein coding gene Chr8:70028686-70050532 (+)
NOD/ShiLtJ ENSMUSG00190009666
 protein coding gene Chr8:60194046-60215912 (+)
NZO/HlLtJ ENSMUSG00225047659
 protein coding gene Chr8:73447490-73469345 (+)
PWK/PhJ ENSLUMG00010012829
 protein coding gene Chr8:60116219-60138070 (+)
SPRET/EiJ ENSMSPG00010030645
 protein coding gene Chr8:61381281-61408912 (+)
WSB/EiJ ENSIUOG00005025424
 protein coding gene Chr8:61115618-61137468 (+)



Homology
more
  • Human Ortholog
    TMEM192, transmembrane protein 192
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM192, transmembrane protein 192
  • Links
    NCBI Gene ID: 201931
    UniProt: Q8IY95

  • Chr Location
    4q32.3; chr4:165070608-165208549 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a knock-put allele are viable and overtly normal with no signs of pathology or lysosomal dysfunction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    34
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025521 Ensembl Gene Model | MGI Sequence Detail 21849 C57BL/6J ±  kb
transcript ENSMUST00000026595 Ensembl | MGI Sequence Detail 1122 Not Applicable  
polypeptide ENSMUSP00000026595 Ensembl | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:256294 Nguyen TL, et al., Functional characterization of the lysosomal membrane protein TMEM192 in mice. Oncotarget. 2017 Jul 4;8(27):43635-43652
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory