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Zcchc12 Gene Detail
Summary
  • Symbol
    Zcchc12
  • Name
    zinc finger, CCHC domain containing 12
  • Synonyms
    2810028A01Rik, Sizn1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919943
    NCBI Gene: 72693
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:35459557-35462811 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 20.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    99 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919943
 protein coding gene ChrX:35459553-35462817 (+)
129S1/SvImJ ENSMUSG00200015120
 protein coding gene ChrX:19567352-19570606 (+)
A/J ENSMUSG00195024970
 protein coding gene ChrX:22239416-22242672 (+)
AKR/J ENSMUSG00220017947
 protein coding gene ChrX:19351664-19354918 (+)
BALB/cJ ENSMUSG00180021596
 protein coding gene ChrX:19797746-19801001 (+)
C3H/HeJ ENSMUSG00175024130
 protein coding gene ChrX:22939946-22943202 (+)
C57BL/6NJ ENSMUSG00215016622
 protein coding gene ChrX:19991729-19994983 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032985
 protein coding gene ChrX:29335700-29339000 (+)
CAST/EiJ ENSTCUG00005031410
 protein coding gene ChrX:21873385-21876640 (+)
CBA/J ENSMUSG00210034724
 protein coding gene ChrX:20233702-20236956 (+)
DBA/2J ENSMUSG00185023760
 protein coding gene ChrX:30816751-30820007 (+)
FVB/NJ ENSMUSG00205018251
 protein coding gene ChrX:18916063-18919318 (+)
JF1/MsJ ENSUMUG00000021925
 protein coding gene ChrX:49944185-49947428 (+)
LP/J ENSMUSG00230012814
 protein coding gene ChrX:37309082-37312337 (+)
NOD/ShiLtJ ENSMUSG00190025490
 protein coding gene ChrX:19506373-19509628 (+)
NZO/HlLtJ ENSMUSG00225039035
 protein coding gene ChrX:42515456-42518710 (+)
PWK/PhJ ENSLUMG00010015529
 protein coding gene ChrX:19652230-19655477 (+)
SPRET/EiJ ENSMSPG00010017235
 protein coding gene ChrX:20874887-20877261 (+)
WSB/EiJ ENSIUOG00005036441
 protein coding gene ChrX:20426540-20429794 (+)



Homology
more
  • Human Ortholog
    ZCCHC12, zinc finger CCHC-type containing 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZCCHC12, zinc finger CCHC-type containing 12
  • Synonyms
    PNMA7A, SIZN, SIZN1
  • Links
    NCBI Gene ID: 170261
    UniProt: Q6PEW1

  • Chr Location
    Xq24; chrX:118823824-118826968 (+)  GRCh38
  • Human Ortholog
    ZCCHC18, zinc finger CCHC-type containing 18
  • Synonyms
    PNMA7B, SIZN2
  • Links
    NCBI Gene ID: 644353
    UniProt: P0CG32

  • Chr Location
    Xq22.2; chrX:104112060-104115847 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    964
  • Tissues
    81
  • cDNA Data
    29
  • Literature Summary
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036699 Ensembl Gene Model | MGI Sequence Detail 3255 C57BL/6J ±  kb
transcript ENSMUST00000115258 Ensembl | MGI Sequence Detail 2181 Not Applicable  
polypeptide ENSMUSP00000110913 Ensembl | MGI Sequence Detail 402 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 29
    Primer pair 2
    Other 1
    Antibodies 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147978
References
more
  • Summaries
    All 45
    Developmental Gene Expression 17
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:373141 Aranda ML, et al., Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior. Nat Commun. 2025 Sep 30;16(1):8678
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory