About   Help   FAQ
Proser1 Gene Detail
Summary
  • Symbol
    Proser1
  • Name
    proline and serine rich 1
  • Synonyms
    2810046L04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919933
    NCBI Gene: 212127
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:53371216-53389176 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 25.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    661 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919933
 protein coding gene Chr3:53371087-53389176 (+)
129S1/SvImJ ENSMUSG00200000335
 protein coding gene Chr3:50214377-50232465 (+)
A/J ENSMUSG00195000678
 protein coding gene Chr3:50158468-50176559 (+)
AKR/J ENSMUSG00220015675
 protein coding gene Chr3:50214621-50232713 (+)
BALB/cJ ENSMUSG00180000374
 protein coding gene Chr3:50238582-50256681 (+)
C3H/HeJ ENSMUSG00175002086
 protein coding gene Chr3:50072964-50091043 (+)
C57BL/6NJ ENSMUSG00215000501
 protein coding gene Chr3:50515481-50533575 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024984
 protein coding gene Chr3:47064419-47082888 (+)
CAST/EiJ ENSTCUG00005009505
 protein coding gene Chr3:49871058-49889088 (+)
CBA/J ENSMUSG00210000485
 protein coding gene Chr3:50194363-50212451 (+)
DBA/2J ENSMUSG00185000228
 protein coding gene Chr3:50415105-50433180 (+)
FVB/NJ ENSMUSG00205009319
 protein coding gene Chr3:49393339-49411424 (+)
JF1/MsJ ENSUMUG00000018287
 protein coding gene Chr3:49835162-49853201 (+)
LP/J ENSMUSG00230004511
 protein coding gene Chr3:52376710-52394793 (+)
NOD/ShiLtJ ENSMUSG00190028677
 protein coding gene Chr3:50547803-50565901 (+)
NZO/HlLtJ ENSMUSG00225016536
 protein coding gene Chr3:54988527-55006617 (+)
PWK/PhJ ENSLUMG00010009426
 protein coding gene Chr3:49973143-49991221 (+)
SPRET/EiJ ENSMSPG00010007148
 protein coding gene Chr3:50684275-50701359 (+)
WSB/EiJ ENSIUOG00005000427
 protein coding gene Chr3:50327054-50345180 (+)



Homology
more
  • Human Ortholog
    PROSER1, proline and serine rich 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PROSER1, proline and serine rich 1
  • Synonyms
    C13orf23
  • Links
    NCBI Gene ID: 80209
    UniProt: Q86XN7

  • Chr Location
    13q13.3; chr13:39009865-39038096 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    52
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 212127 NCBI Gene Model | MGI Sequence Detail 17961 C57BL/6J ±  kb
transcript NM_173382 RefSeq | MGI Sequence Detail 4343 C57BL/6  
polypeptide Q5PRE5 UniProt | EBI | MGI Sequence Detail 913 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Diseases 1
    Phenotypes 14
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:366946 Fleming A, et al., PROSER1 modulates DNA demethylation through dual mechanisms to prevent syndromic developmental malformations. Genes Dev. 2024 Nov 27;38(21-24):952-964
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory