Adipor1 MGI Mouse Gene Detail - MGI:1919924

Symbol

Adipor1
Name

adiponectin receptor 1
Synonyms

2810031L11Rik

Feature Type

protein coding gene
IDs

MGI:1919924
NCBI Gene: 72674
Alliance

genome feature page
Transcription Start Sites

11 TSS

Sequence Map

Chr1:134343116-134361089 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 58.22 cM, cytoband E4
Mapping Data

2 experiments

SNPs within 2kb

493 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919924	protein coding gene	Chr1:134343116-134361089 (+)
129S1/SvImJ	ENSMUSG00200008743	protein coding gene	Chr1:131941976-131959949 (+)
A/J	ENSMUSG00195039324	protein coding gene	Chr1:131016670-131034613 (+)
AKR/J	ENSMUSG00220044992	protein coding gene	Chr1:130886725-130904679 (+)
BALB/cJ	ENSMUSG00180033982	protein coding gene	Chr1:131570473-131588446 (+)
C3H/HeJ	ENSMUSG00175041715	protein coding gene	Chr1:131260899-131278841 (+)
C57BL/6NJ	ENSMUSG00215044990	protein coding gene	Chr1:131272140-131290114 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014622	protein coding gene	Chr1:126010888-126028846 (+)
CAST/EiJ	ENSTCUG00005032788	protein coding gene	Chr1:130179389-130197411 (+)
CBA/J	ENSMUSG00210027658	protein coding gene	Chr1:131192327-131210289 (+)
DBA/2J	ENSMUSG00185027477	protein coding gene	Chr1:135553439-135571393 (+)
FVB/NJ	ENSMUSG00205042771	protein coding gene	Chr1:130518726-130536680 (+)
JF1/MsJ	ENSUMUG00000027515	protein coding gene	Chr1:134703642-134721615 (+)
LP/J	ENSMUSG00230033898	protein coding gene	Chr1:135105322-135123299 (+)
NOD/ShiLtJ	ENSMUSG00190037127	protein coding gene	Chr1:131206431-131224389 (+)
NZO/HlLtJ	ENSMUSG00225019325	protein coding gene	Chr1:138856777-138874719 (+)
PWK/PhJ	ENSLUMG00010024094	protein coding gene	Chr1:130328877-130346791 (+)
SPRET/EiJ	ENSMSPG00010039834	protein coding gene	Chr1:133130878-133147871 (+)
WSB/EiJ	ENSIUOG00005041832	protein coding gene	Chr1:130941039-130958993 (+)

Human Ortholog

ADIPOR1, adiponectin receptor 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ADIPOR1, adiponectin receptor 1
Synonyms

ACDCR1, CGI-45, CGI45, PAQR1, TESBP1A
Links

HGNC:24040

NCBI Gene ID: 51094

UniProt: Q96A54
Chr Location

1q32.1; chr1:202940090-202958572 (-) GRCh38

MGI Vertebrate Homology

Adipor1 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: ADIPOR1
Gene Tree

Adipor1

Diseases

3 with human ADIPOR1 associations

				Human Disease	Mouse Models
				breast cancer IDs breast cancer DOID:1612 DOID:1648 DOID:4241 ICD10CM:C50 ICD9CM:174.8 MESH:D001943 NCI:C9335 OMIM:114480 UMLS_CUI:C0006142
				macular degeneration IDs macular degeneration DOID:4448 MESH:D008268 NCI:C123330 ORDO:279 UMLS_CUI:C0024437
				prostate adenocarcinoma IDs prostate adenocarcinoma DOID:2526 NCI:C2919 UMLS_CUI:C0007112

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

47 phenotypes from 4 alleles in 7 genetic backgrounds
10 phenotypes from multigenic genotypes
56 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

51
Chemically induced (other)

2
Endonuclease-mediated

8
Gene trapped

30
Radiation induced

1
Targeted

10
Genomic Mutations

3 involving Adipor1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

45 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a targeted allele exhibit abnormal homeostasis, adipose tissue morphology and adaptive thermogenesis.

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All GO Annotations

58
GO References

13

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

869
Tissues

141
cDNA Data

229
Literature Summary

13

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase adipor1

ZFIN adipor1a, adipor1b

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All Sequences

87
RefSeq

4
UniProt

4
CCDS

CCDS15309.1

Ensembl

ENSMUSG00000026457 (Evidence)
NCBI Gene

72674

			Length	Strain/Species	Flank
genomic	72674	NCBI Gene Model \| MGI Sequence Detail	17974	C57BL/6J	± kb
transcript	NM_001306069	RefSeq \| MGI Sequence Detail	3132	C57BL/6
polypeptide	Q91VH1	UniProt \| EBI \| MGI Sequence Detail	375	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000003778 adiponectin receptor protein 1

(term hierarchy)
InterPro Domains

IPR004254 AdipoR/Haemolysin-III-related

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All nucleic 235

cDNA 230

Primer pair 5

Antibodies 1

Microarray probesets 5

Summaries

All 124

Developmental Gene Expression 13

Gene Ontology 13

Phenotypes 56
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:369775 Lindfors S, et al., Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon Adiponectin Receptor 1 Depletion. J Am Soc Nephrol. 2025 May 1;36(5):825-844

TSS for Adipor1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8885	Chr1:134343126-134343133 (+)	14 bp
Tssr8886	Chr1:134343134-134343146 (+)	24 bp
Tssr8887	Chr1:134343152-134343242 (+)	81 bp
Tssr8888	Chr1:134343248-134343272 (+)	144 bp
Tssr8889	Chr1:134343448-134343523 (+)	370 bp
Tssr8890	Chr1:134351733-134351765 (+)	8,633 bp
Tssr8891	Chr1:134352493-134352513 (+)	9,387 bp
Tssr8892	Chr1:134355853-134355893 (+)	12,757 bp
Tssr8893	Chr1:134358885-134358949 (+)	15,801 bp
Tssr8894	Chr1:134359733-134359762 (+)	16,632 bp
Tssr8895	Chr1:134359936-134359947 (+)	16,826 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29