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Mettl28 Gene Detail
Summary
  • Symbol
    Mettl28
  • Name
    methyltransferase like 28
  • Synonyms
    2700097O09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919908
    NCBI Gene: 72658
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:55092446-55126895 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 23.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    947 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919908
 protein coding gene Chr12:55092446-55127256 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019742
 protein coding gene Chr12:54003485-54248793 (-)
A/J MGP_AJ_G0019704
 protein coding gene Chr12:52112761-52130326 (-)
AKR/J MGP_AKRJ_G0019675
 protein coding gene Chr12:53665326-53929698 (-)
BALB/cJ MGP_BALBcJ_G0019682
 protein coding gene Chr12:52394700-52429991 (-)
C3H/HeJ MGP_C3HHeJ_G0019485
 protein coding gene Chr12:53782152-54018695 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020130
 protein coding gene Chr12:55667688-55706936 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017753
 protein coding gene Chr12:50369730-50404591 (-)
CAST/EiJ MGP_CASTEiJ_G0019038
 protein coding gene Chr12:48794670-48859930 (-)
CBA/J MGP_CBAJ_G0019457
 protein coding gene Chr12:57583690-57815279 (-)
DBA/2J MGP_DBA2J_G0019571
 protein coding gene Chr12:51953088-51987893 (-)
FVB/NJ MGP_FVBNJ_G0019560
 protein coding gene Chr12:51368563-51406977 (-)
LP/J MGP_LPJ_G0019643
 protein coding gene Chr12:54066692-54102995 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019596
 protein coding gene Chr12:59181128-59419725 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020168
 protein coding gene Chr12:53155126-53257163 (-)
PWK/PhJ MGP_PWKPhJ_G0018805
 protein coding gene Chr12:46529158-46564802 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018599
 protein coding gene Chr12:47747718-47770675 (-)
WSB/EiJ MGP_WSBEiJ_G0019089
 protein coding gene Chr12:53631812-53862404 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    869
  • Tissues
    48
  • cDNA Data
    30
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000062198 Ensembl Gene Model | MGI Sequence Detail 34450 C57BL/6J ±  kb
    transcript ENSMUST00000021406 Ensembl | MGI Sequence Detail 1105 Not Applicable  
    polypeptide ENSMUSP00000021406 Ensembl | MGI Sequence Detail 301 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR026669 Arsenite methyltransferase-like
      IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145041, MGI:8270704
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/09/2026
    MGI 6.24     		The Jackson Laboratory