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Ppp1r14d Gene Detail
Summary
  • Symbol
    Ppp1r14d
  • Name
    protein phosphatase 1, regulatory inhibitor subunit 14D
  • Synonyms
    2010107K19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919362
    NCBI Gene: 72112
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119048600-119060387 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 59.97 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    440 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919362
 protein coding gene Chr2:119048600-119060557 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026337
 protein coding gene Chr2:121955374-121967033 (-)
A/J MGP_AJ_G0026298
 protein coding gene Chr2:116994557-117006102 (-)
AKR/J MGP_AKRJ_G0026277
 protein coding gene Chr2:120271985-120283670 (-)
BALB/cJ MGP_BALBcJ_G0026311
 protein coding gene Chr2:117257976-117271063 (-)
C3H/HeJ MGP_C3HHeJ_G0026057
 protein coding gene Chr2:120737830-120750753 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026758
 protein coding gene Chr2:125969757-125982148 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024138
 protein coding gene Chr2:112046729-112059678 (-)
CAST/EiJ MGP_CASTEiJ_G0025519
 protein coding gene Chr2:121046252-121059551 (-)
CBA/J MGP_CBAJ_G0026033
 protein coding gene Chr2:130401536-130417922 (-)
DBA/2J MGP_DBA2J_G0026172
 protein coding gene Chr2:116419929-116431703 (-)
FVB/NJ MGP_FVBNJ_G0026134
 protein coding gene Chr2:115238717-115251411 (-)
LP/J MGP_LPJ_G0026273
 protein coding gene Chr2:122270696-122282151 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026153
 protein coding gene Chr2:134754241-134767153 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026813
 protein coding gene Chr2:120390164-120403230 (-)
PWK/PhJ MGP_PWKPhJ_G0025255
 protein coding gene Chr2:115978627-115991333 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025054
 protein coding gene Chr2:119578230-119593185 (-)
WSB/EiJ MGP_WSBEiJ_G0025588
 protein coding gene Chr2:121226118-121240274 (-)



Homology
more
  • Human Ortholog
    PPP1R14D, protein phosphatase 1 regulatory inhibitor subunit 14D
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R14D, protein phosphatase 1 regulatory inhibitor subunit 14D
  • Synonyms
    CPI17-like, GBPI-1, GBPI1
  • Links
    NCBI Gene ID: 54866
    UniProt: Q9NXH3

  • Chr Location
    15q15.1; chr15:40815451-40828709 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027317 Ensembl Gene Model | MGI Sequence Detail 11788 C57BL/6J ±  kb
    transcript ENSMUST00000110820 Ensembl | MGI Sequence Detail 790 Not Applicable  
    polypeptide ENSMUSP00000106444 Ensembl | MGI Sequence Detail 175 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Gene Ontology 2
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory